☆ 4.8 Article

CaCO3 nanoparticles incorporated with KAE to enable amplified calcium overload cancer therapy

BIOMATERIALS (2021)

相关参考文献

注意：仅列出部分参考文献，下载原文获取全部文献信息。

Article Engineering, Biomedical

Energy expenditure during cell spreading influences the cellular response to matrix stiffness

Jing Xie et al.

Summary: Cells respond to mechanical cues from the extracellular matrix by adjusting their cytoskeleton and forming focal adhesions, which can lead to changes in ATP levels and activation of AMPK. This can affect cell spreading and tension, as well as influence stem cell fate in response to ECM mechanics. Lowered ATP levels on softer substrates limit cellular mechanoresponses.

BIOMATERIALS (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Ultrasound-Augmented Mitochondrial Calcium Ion Overload by Calcium Nanomodulator to Induce Immunogenic Cell Death

Pan Zheng et al.

Summary: This study developed an acid-sensitive nanoparticle ((CaCUR)-Ca-PEG) that induces mitochondrial Ca2+ overload and acts as an ICD inducer in improved cancer therapy. Combination with ultrasound (US) enhances the ICD effect, showing promising therapeutic and diagnostic properties.

NANO LETTERS (2021)

添加到收藏夹

Review Cell Biology

Cofilin: A Promising Protein Implicated in Cancer Metastasis and Apoptosis

Jing Xu et al.

Summary: Cofilin is a protein that plays a crucial role in cancer metastasis by regulating cytoskeletal reorganization and other processes. Clinical studies have explored the relationship between cofilin, tumor cells apoptosis, and cofilin-related miRNAs.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

添加到收藏夹

Article Chemistry, Medicinal

A CaO2@Tannic Acid-FeIII Nanoconjugate for Enhanced Chemodynamic Tumor Therapy

Fei Chen et al.

Summary: A new nano-system CaO2@TA-Fe-III was designed and synthesized to enhance CDT by solving the issues of insufficient H2O2 content and low catalytic efficiency in the Fenton reaction in tumor treatment. The nanoconjugates effectively killed cancer cells and displayed excellent tumor therapeutic effects, showing promise as a new nano-platform for highly effective tumor treatment.

CHEMMEDCHEM (2021)

添加到收藏夹

Article Chemistry, Medicinal

Polymerized Albumin Receptor of Hepatitis B Virus for Evading the Reticuloendothelial System

Kurumi Takagi et al.

Summary: The study investigated the surface modification of bio-nanocapsules (BNCs) with polymerized albumin receptors (PAR) to enhance their evasion of the reticuloendothelial system (RES) in mouse liver. Results showed that peptides conjugated with sufficient PAR activity on nanoparticles reduced capture by Kupffer cells and prolonged circulation time in vivo. This suggests that PAR peptides could be an alternative strategy for improving the pharmacodynamics and pharmacokinetics of future nanomedicines.

PHARMACEUTICALS (2021)

添加到收藏夹

Article Materials Science, Ceramics

Facile synthesis of Mg-doped calcium silicate porous nanoparticles for targeted drug delivery and ovarian cancer treatment

Hanwei Cui et al.

Summary: Chemotherapic cancer treatment has been limited by side effects and lack of target specificity. pH-triggered drug delivery systems can improve drug delivery to cancer cells. The synthesis of highly porous CaMgSiO4 nanospheres with uniform Mg doping shows promise for pH-responsive drug delivery. Characterizations showed increased surface area and drug loading capacity, with pH-triggered drug release and high cytotoxicity to cancer cells.

CERAMICS INTERNATIONAL (2021)

添加到收藏夹

Review Chemistry, Multidisciplinary

Bio-based nanomaterials for cancer therapy

Yonglu Li et al.

Summary: This study discusses the importance of bio-based nanomaterials in cancer therapy and their applications in breast cancer treatment, focusing on the functional classification of different bioactive substances and the characteristic performance of nano-systems.

NANO TODAY (2021)

添加到收藏夹

Article Food Science & Technology

Apios Americana Medicus: A potential staple food candidate with versatile bioactivities

Yonglu Li et al.

Summary: AM has abundant bioactive chemicals in different parts and demonstrates remarkable bioactivities. The research focused on AM's nutritional values and biological activities while also discussing the present shortage and challenges. AM shows potential to become a future staple food candidate with diverse bioactivities, providing potential promising strategies to solve global hunger.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2021)

添加到收藏夹

Article Chemistry, Multidisciplinary

Cu-Ferrocene-Functionalized CaO2 Nanoparticles to Enable Tumor-Specific Synergistic Therapy with GSH Depletion and Calcium Overload

Hanjing Kong et al.

Summary: The study successfully designed and synthesized fine CaO2 nanoparticles with Cu-ferrocene molecules on the surface, which release Ca2+ ions and H2O2 under acidic conditions and promote the production of (OH)-O-center dot. The enhanced (OH)-O-center dot induction and intracellular calcium overload contribute significantly to antitumor effects in vitro and in vivo.

ADVANCED SCIENCE (2021)

添加到收藏夹

Article Food Science & Technology

Tetrastigma hemsleyanum leaf flavones have anti-NSCLC ability by triggering apoptosis using the Akt-mTOR pathway

Yonglu Li et al.

Summary: The study showed that TLF extracted from the leaf part of Tetrastigma hemsleyanum inhibited the proliferation and migration of non-small cell lung cancer cells, induced apoptosis, and potential as an anti-NSCLC drug candidate.

FOOD BIOSCIENCE (2021)

添加到收藏夹

Article Biochemistry & Molecular Biology

Kaempferol-3-O-rutinoside, a flavone derived from Tetrastigma hemsleyanum, suppresses lung adenocarcinoma via the calcium signaling pathway

Yonglu Li et al.

Summary: The study demonstrated that Tetrastigma hemsleyanum tuber flavonoids (THTF) could effectively suppress lung adenocarcinoma cell viability by inducing apoptosis through cytoskeleton collapse, mitochondrial dysfunction, and calcium overload. Proteomic analysis supported the in vitro findings, suggesting THTF and its major component kaempferol-3-O-rutinoside (K3R) as promising anti-cancer agents for lung cancer prevention and therapy.

FOOD & FUNCTION (2021)

添加到收藏夹

Review Engineering, Biomedical

Tumor microenvironment targeted nanotherapeutics for cancer therapy and diagnosis: A review

Shreya Thakkar et al.

ACTA BIOMATERIALIA (2020)

添加到收藏夹

Article Biophysics

Resveratrol-loaded chitosan-γ-poly(glutamic acid) nanoparticles: Optimization, solubility, UV stability, and cellular antioxidant activity

Joo Hee Chung et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2020)

添加到收藏夹

Article Biochemistry & Molecular Biology

Russula alutacea Fr. polysaccharide ameliorates inflammation in both RAW264.7 and zebrafish (Danio rerio) larvae

Yonglu Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)

添加到收藏夹

Review Biotechnology & Applied Microbiology

Cell membrane-coated nanoparticles: research advances

Shuaijun Zou et al.

NANOMEDICINE (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Nanoenabled Disruption of Multiple Barriers in Antigen Cross-Presentation of Dendritic Cells via Calcium Interference for Enhanced Chemo-Immunotherapy

Jingyi An et al.

ACS NANO (2020)

添加到收藏夹

Article Chemistry, Multidisciplinary

Calcium Phosphate Mineralized Black Phosphorous with Enhanced Functionality and Anticancer Bioactivity

Ting Pan et al.

ADVANCED FUNCTIONAL MATERIALS (2020)

添加到收藏夹

Article Chemistry, Applied

Fast-dissolving antioxidant curcumin/cyclodextrin inclusion complex electrospun nanofibrous webs

Asli Celebioglu et al.

FOOD CHEMISTRY (2020)

添加到收藏夹

Article Chemistry, Applied

Impact of oil type on the location, partition and chemical stability of resveratrol in oil-in-water emulsions stabilized by whey protein isolate plus gum Arabic

Hao Cheng et al.

FOOD HYDROCOLLOIDS (2020)

添加到收藏夹

Article Materials Science, Biomaterials

Delivery of amino acid oxidaseviacatalytic nanocapsules to enable effective tumor inhibition

Qiang Chu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

添加到收藏夹

Review Biochemistry & Molecular Biology

Mechanical tumor microenvironment and transduction: cytoskeleton mediates cancer cell invasion and metastasis

Xingchen Li et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2020)

添加到收藏夹

Article Cell Biology

Ultrastructure and dynamics of the actin-myosin II cytoskeleton during mitochondrial fission

Changsong Yang et al.

NATURE CELL BIOLOGY (2019)

添加到收藏夹

Article Multidisciplinary Sciences

Cofilin drives rapid turnover and fluidization of entangled F-actin

Patrick M. McCall et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

添加到收藏夹

Article Biochemistry & Molecular Biology

Mitochondrial morphology regulates organellar Ca2+ uptake and changes cellular Ca2+ homeostasis

Alicia J. Kowaltowski et al.

FASEB JOURNAL (2019)

添加到收藏夹

Review Biochemistry & Molecular Biology

Bioactivities, isolation and purification methods of polysaccharides from natural products: A review

Lei Shi

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2016)

添加到收藏夹

Review Food Science & Technology

Resveratrol encapsulation: Designing delivery systems to overcome solubility, stability and bioavailability issues

Gabriel Davidov-Pardo et al.

TRENDS IN FOOD SCIENCE & TECHNOLOGY (2014)

添加到收藏夹

Article Chemistry, Physical

Polymeric micelles for parenteral delivery of curcumin: Preparation, characterization and in vitro evaluation

Lei Song et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2011)

添加到收藏夹

© Peeref 2019-2024. All rights reserved.