4.7 Article

SteadyCellPhenotype: a web-based tool for the modeling of biological networks with ternary logic

期刊

BIOINFORMATICS
卷 38, 期 8, 页码 2369-2370

出版社

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btac097

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资金

  1. CAS Mellon Fund at American University
  2. NIH [1U01EB024501-01, 1R01AI135128-01, 1R01GM127909-01]
  3. NSF [CBET-1750183]

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Introducing SteadyCellPhenotype, a browser-based interface for analyzing ternary biological networks. It provides tools for deterministically finding all steady states of a network and simulating and visualizing trajectories with high-quality graphics for publication. Simulations help approximate the size of attractor basins, while deterministic simulations of trajectories near specified points allow exploration of the system's behavior in that neighborhood.
We introduce SteadyCellPhenotype, a browser-based interface for the analysis of ternary biological networks. It includes tools for deterministically finding all steady states of a network, as well as the simulation and visualization of trajectories with publication quality graphics. Simulations allow us to approximate the size of the basin for attractors and deterministic simulations of trajectories nearby specified points allow us to explore the behavior of the system in that neighborhood.

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