4.4 Article

Geroscience: the need to address some issues

期刊

BIOGERONTOLOGY
卷 23, 期 1, 页码 145-150

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SPRINGER
DOI: 10.1007/s10522-022-09951-4

关键词

Geroscience; Healthspan; Lifespan

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The geroscience field suggests that delaying the ageing process itself could potentially delay all age-related diseases, instead of individually treating each disease. However, there are some issues that temporarily hinder full adherence to this perspective, such as the risk of over-enthusiasm or scientism, and the assumption that animal model results can easily be applied to humans.
The geroscience field hypothesises that it could be possible to delay all age-related diseases by delaying the ageing process itself, and not by curing each age-related disease individually. While this perspective is attracting, some issues provisionally prohibit to fully adhere to it, such as the risk for some over-enthusiasm or scientism and the tendency to accept that results observed in animal models can be easily translated in human beings. Particularly, it is not clear whether geroscience plans to delay or suppress ageing, or if healthspan could become very close to lifespan. This article lists some of these issues, in the hope that supporters of geroscience will grasp them to allow a full development of the field, and argues that geroscience should avoid reductionist approaches not taking into account social and behavioural complex aspects of human ageing.

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