Chemical constituents of Euphorbia peplus

Phytochemical investigation of the whole plant of Euphorbia peplus Linn. led to the isolation of previously uncharacterized jatrophane type diterpenoid euphopepluanone L (1), along with seven known compounds, including three diterpenes (2-4), three bisnorsesquiterpenes (5-7), and a monoterpene (8). Their chemical structures were established based on extensive spectroscopic analysis. Compounds 3 (20-deoxyingenol) and 5-8 were firstly isolated from E. peplus, while PBI 345 (5) reported from the genus for the first time. Furthermore, the chemotaxonomic significance of the isolates was discussed.

Automated summary

A phytochemical investigation of the whole plant of Euphorbia peplus Linn. led to the isolation of a previously uncharacterized jatrophane type diterpenoid, euphopepluanone L (1), along with seven known compounds. The chemical structures of these compounds were established through extensive spectroscopic analysis, with several compounds being isolated from E. peplus for the first time. The chemotaxonomic significance of the isolates was also discussed.