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JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
A Dimeric PINK1-containing Complex on Depolarized Mitochondria Stimulates Parkin Recruitment
Kei Okatsu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Restricted mitochondrial protein acetylation initiates mitochondrial autophagy
Bradley R. Webster et al.
JOURNAL OF CELL SCIENCE (2013)
The LIR motif - crucial for selective autophagy
Asa Birna Birgisdottir et al.
JOURNAL OF CELL SCIENCE (2013)
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
Shireen A. Sarraf et al.
NATURE (2013)
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
Samuel A. Hasson et al.
NATURE (2013)
Autophagosomes form at ER-mitochondria contact sites
Maho Hamasaki et al.
NATURE (2013)
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
G. M. Tannahill et al.
NATURE (2013)
Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells
Charleen T. Chu et al.
NATURE CELL BIOLOGY (2013)
Amino acid signalling upstream of mTOR
Jenna L. Jewell et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2013)
Structure of Parkin Reveals Mechanisms for Ubiquitin Ligase Activation
Jean-Francois Trempe et al.
SCIENCE (2013)
PINK1-Phosphorylated Mitofusin 2 Is a Parkin Receptor for Culling Damaged Mitochondria
Yun Chen et al.
SCIENCE (2013)
Selective escape of proteins from the mitochondria during mitophagy
Shotaro Saita et al.
NATURE COMMUNICATIONS (2013)
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
B. E. Riley et al.
NATURE COMMUNICATIONS (2013)
Sulfhydration mediates neuroprotective actions of parkin
M. Scott Vandiver et al.
NATURE COMMUNICATIONS (2013)
ER-associated mitochondrial division links the distribution of mitochondria and mitochondrial DNA in yeast
Andrew Murley et al.
ELIFE (2013)
Increased endogenous H2S generation by CBS, CSE, and 3MST gene therapy improves ex vivo renovascular relaxation in hyperhomocysteinemia
Utpal Sen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2012)
ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy
Yuqing Wang et al.
AUTOPHAGY (2012)
A Quantitative Map of the Liver Mitochondrial Phosphoproteome Reveals Posttranslational Control of Ketogenesis
Paul A. Grimsrud et al.
CELL METABOLISM (2012)
The NAD+ Precursor Nicotinamide Riboside Enhances Oxidative Metabolism and Protects against High-Fat Diet-Induced Obesity
Caries Canto et al.
CELL METABOLISM (2012)
SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function
Nathan L. Price et al.
CELL METABOLISM (2012)
A Vesicular Transport Pathway Shuttles Cargo from Mitochondria to Lysosomes
Vincent Soubannier et al.
CURRENT BIOLOGY (2012)
Role of PINK1 Binding to the TOM Complex and Alternate Intracellular Membranes in Recruitment and Activation of the E3 Ligase Parkin
Michael Lazarou et al.
DEVELOPMENTAL CELL (2012)
Bcl-rambo induces apoptosis via interaction with the adenine nucleotide translocator
Jee-Youn Kim et al.
FEBS LETTERS (2012)
Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1
M. Paulina Ordonez et al.
HUMAN MOLECULAR GENETICS (2012)
Microtubule-associated Protein 1 Light Chain 3 (LC3) Interacts with Bnip3 Protein to Selectively Remove Endoplasmic Reticulum and Mitochondria via Autophagy
Rita A. Hanna et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Nicotinamide-induced Mitophagy EVENT MEDIATED BY HIGH NAD+/NADH RATIO AND SIRT1 PROTEIN ACTIVATION
So-young Jang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Physiological Roles of Mitochondrial Reactive Oxygen Species
Laura A. Sena et al.
MOLECULAR CELL (2012)
MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism
Karthik Mallilankaraman et al.
NATURE CELL BIOLOGY (2012)
Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells
Lei Liu et al.
NATURE CELL BIOLOGY (2012)
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
R. David Sentelle et al.
NATURE CHEMICAL BIOLOGY (2012)
Endoplasmic reticulum-mitochondria contacts: function of the junction
Ashley A. Rowland et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Mitochondria as sensors and regulators of calcium signalling
Rosario Rizzuto et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
PHYSIOLOGICAL IMPLICATIONS OF HYDROGEN SULFIDE: A WHIFF EXPLORATION THAT BLOSSOMED
Rui Wang
PHYSIOLOGICAL REVIEWS (2012)
High-Glucose Stimulation Increases Reactive Oxygen Species Production Through the Calcium and Mitogen-Activated Protein Kinase-Mediated Activation of Mitochondrial Fission
Tianzheng Yu et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease
Joo-Ho Shin et al.
CELL (2011)
PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility
Xinnan Wang et al.
CELL (2011)
Mitochondrially localized PKA reverses mitochondrial pathology and dysfunction in a cellular model of Parkinson's disease
R. K. Dagda et al.
CELL DEATH AND DIFFERENTIATION (2011)
Secondary coenzyme Q10 deficiency triggers mitochondria degradation by mitophagy in MELAS fibroblasts
David Cotan et al.
FASEB JOURNAL (2011)
PINK1 cleavage at position A103 by the mitochondrial protease PARL
Emma Deas et al.
HUMAN MOLECULAR GENETICS (2011)
Muscle choline kinase beta defect causes mitochondrial dysfunction and increased mitophagy
Satomi Mitsuhashi et al.
HUMAN MOLECULAR GENETICS (2011)
Stabilization of Suv39H1 by SirT1 Is Part of Oxidative Stress Response and Ensures Genome Protection
Laia Bosch-Presegue et al.
MOLECULAR CELL (2011)
Complex Inhibitory Effects of Nitric Oxide on Autophagy
Sovan Sarkar et al.
MOLECULAR CELL (2011)
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
Ligia C. Gomes et al.
NATURE CELL BIOLOGY (2011)
Identification of lysine succinylation as a new post-translational modification
Zhihong Zhang et al.
NATURE CHEMICAL BIOLOGY (2011)
Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
Angelika S. Rambold et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
Daniel F. Egan et al.
SCIENCE (2011)
ER Tubules Mark Sites of Mitochondrial Division
Jonathan R. Friedman et al.
SCIENCE (2011)
Bnip3-mediated mitochondrial autophagy is independent of the mitochondrial permeability transition pore
Melissa N. Quinsay et al.
AUTOPHAGY (2010)
Control of basal autophagy by calpain1 mediated cleavage of ATG5
Hong-guang Xia et al.
AUTOPHAGY (2010)
Essential Regulation of Cell Bioenergetics by Constitutive InsP3 Receptor Ca2+ Transfer to Mitochondria
Cesar Cardenas et al.
CELL (2010)
Nix is a selective autophagy receptor for mitochondrial clearance
Ivana Novak et al.
EMBO REPORTS (2010)
Regulation of the autophagy protein LC3 by phosphorylation
Salvatore J. Cherra et al.
JOURNAL OF CELL BIOLOGY (2010)
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
Seok Min Jin et al.
JOURNAL OF CELL BIOLOGY (2010)
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
Sven Geisler et al.
NATURE CELL BIOLOGY (2010)
Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol
Des R. Richardson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Ammonia Derived from Glutaminolysis Is a Diffusible Regulator of Autophagy
Christina H. Eng et al.
SCIENCE SIGNALING (2010)
Nicotinamide enhances mitochondria quality through autophagy activation in human cells
Hyun Tae Kang et al.
AGING CELL (2009)
Nix directly binds to GABARAP A possible crosstalk between apoptosis and autophagy
Melanie Schwarten et al.
AUTOPHAGY (2009)
Coenzyme Q deficiency triggers mitochondria degradation by mitophagy
Angeles Rodriguez-Hernandez et al.
AUTOPHAGY (2009)
The Mechanism of Ca2+-Dependent Regulation of Kinesin-Mediated Mitochondrial Motility
Xinnan Wang et al.
CELL (2009)
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy
J. Zhang et al.
CELL DEATH AND DIFFERENTIATION (2009)
Atg32 Is a Mitochondrial Protein that Confers Selectivity during Mitophagy
Tomotake Kanki et al.
DEVELOPMENTAL CELL (2009)
Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
Koji Okamoto et al.
DEVELOPMENTAL CELL (2009)
Glutathione Participates in the Regulation of Mitophagy in Yeast
Maika Deffieu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Loss of PINK1 Function Promotes Mitophagy through Effects on Oxidative Stress and Mitochondrial Fission
Ruben K. Dagda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Regulation of glutathione synthesis
Shelly C. Lu
MOLECULAR ASPECTS OF MEDICINE (2009)
PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-induced Cell Death
Sonia Gandhi et al.
MOLECULAR CELL (2009)
Induction of autophagy by spermidine promotes longevity
Tobias Eisenberg et al.
NATURE CELL BIOLOGY (2009)
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
Ralph J. DeBerardinis et al.
CELL METABOLISM (2008)
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
Huafeng Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
Derek Narendra et al.
JOURNAL OF CELL BIOLOGY (2008)
Essential role for Nix in autophagic maturation of erythroid cells
Hector Sandoval et al.
NATURE (2008)
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
In Hye Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
Clement A. Gautier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
Yufeng Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The PINK1/Parkin pathway regulates mitochondrial morphology
Angela C. Poole et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
Hansong Deng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
NIX is required for programmed mitochondrial clearance during reticulocyte maturation
Rachel L. Schweers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
FoxO3 controls autophagy in skeletal muscle in vivo
Cristina Mammucari et al.
CELL METABOLISM (2007)
Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
J. Thomas Cribbs et al.
EMBO REPORTS (2007)
BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy
Kristin Tracy et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Lactate sensitive transcription factor network in L6 cells:: activation of MCT1 and mitochondrial biogenesis
Takeshi Hashimoto et al.
FASEB JOURNAL (2007)
Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology
Chuang-Rung Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
Julia W. Pridgeon et al.
PLOS BIOLOGY (2007)
Pyruvate induces mitochondrial biogenesis by a PGC-1α-independent mechanism
Leanne Wilson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2007)
Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis
Abhinav Diwan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Selective silencing of the hypoxia-inducible factor 1 target gene BNIP3 by histone deacetylation and methylation in colorectal cancer
A. L. Bacon et al.
ONCOGENE (2007)
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
Ira E. Clark et al.
NATURE (2006)
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
Jeehye Park et al.
NATURE (2006)
Heme oxygenase-1/carbon monoxide: From basic science to therapeutic applications
SW Ryter et al.
PHYSIOLOGICAL REVIEWS (2006)
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer
J Okami et al.
CANCER RESEARCH (2004)
Hyperglycentia regulates hypoxia-inducible factor-1α protein stability and function
SB Catrina et al.
DIABETES (2004)
Sulfur containing amino acids and human disease
DM Townsend et al.
BIOMEDICINE & PHARMACOTHERAPY (2004)
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
JC Greene et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
GABA, gamma-hydroxybutyric acid, and neurological disease
CGT Wong et al.
ANNALS OF NEUROLOGY (2003)
Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis
M Shirane et al.
NATURE CELL BIOLOGY (2003)
Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1
R Marfella et al.
DIABETOLOGIA (2002)
Mitochondrial disappearance from cells: a clue to the role of autophagy in programmed cell death and disease?
AM Tolkovsky et al.
BIOCHIMIE (2002)
Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension
T Kataoka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia
RK Bruick
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
CY Du et al.
CELL (2000)
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