期刊
AUTOPHAGY
卷 18, 期 3, 页码 705-706出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/15548627.2022.2027194
关键词
Autophagic degradation; autophagy; defense; V-ATPase; vacuolar acidification; virus
类别
资金
- Ministry of Science and Technology of the People's Republic of China [2021YFD1400400, 2017YFA0503401]
- National Natural Science Foundation of China [32130086, 31970147, 31920103013]
This article discusses how plant viruses promote infection by interfering with vacuolar acidification and the degradation of autophagic bodies.
Vacuoles are the largest compartments in plant cells and are involved in plant development and response to abiotic and biotic stresses. Vacuolar acidification is essential for vacuoles in various physiological functions. However, its role in plant defense, and whether and how pathogens affect vacuolar acidification to promote infection have never been reported. In this autophagy punctum, we discuss our recent findings about how plant viruses suppress vacuolar acidification and the degradation of autophagic bodies by directly interacting with a component of the V-ATPase to promote virus infection.
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