Synthesis of Phospholipids Under Plausible Prebiotic Conditions and Analogies with Phospholipid Biochemistry for Origin of Life Studies†

Phospholipids are essential components of biological membranes and are involved in cell signalization, in several enzymatic reactions, and in energy metabolism. In addition, phospholipids represent an evolutionary and non-negligible step in life emergence. Progress in the past decades has led to a deeper understanding of these unique hydrophobic molecules and their most pertinent functions in cell biology. Today, a growing interest in prebiotic lipidomics calls for a new assessment of these relevant biomolecules.

Automated summary

Phospholipids are crucial components of biological membranes and play roles in cell signaling, enzymatic reactions, and energy metabolism. They also have significant implications in the emergence of life. Recent advancements have provided a deeper understanding of these unique hydrophobic molecules and their essential functions in cell biology. There is now growing interest in prebiotic lipidomics, calling for a reevaluation of these important biomolecules.