Effect of transanal drainage tube on anastomotic leakage following low anterior resection for rectal cancer without a defunctioning stoma

Purpose: Anastomotic leakage (AL) is one of the most serious complications of rectal cancer surgery. The aim of this study was to analyze the effectiveness and safety of transanal drainage tube (TDT) placement to prevent AL after low anterior resection (LAR) for rectal cancer. Material and method: In this retrospective study, the data of 556 patients with rectal cancer who un-derwent LAR using the double stapling technique between January 2001 and April 2016 were analyzed. The patients were divided two groups: the non-transanal drainage tube (NTDT) group comprised pa-tients without a TDT (n = 341) and the transanal drainage tube (TDT) group, patients with a TDT (n = 215). Results: The overall rate of AL was 4.1% (n = 23). The AL rate was significantly lower in the TDT group. The AL rate was 5.6% (n = 19) in the NTDT group and 1.9% (n = 4) in the TDT group (p = 0.032). The mean time of AL postoperatively was 6.0 days. Among AL patients, the re-operation rate for AL was 84.2% (16/19) for the NTDT group and 75.0% (3/4) for the TDT group. Sex, age, BMI, neoadjuvant chemoradiation therapy, tumor location, and double stapler diameter were not analysized to be risk factors for AL after LAR. Non-use of a TDT (odds ratio, 0.106; 95% confidence interval, 0.013-0.843; p = 0.034) was established as a risk factor for AL in the logistic analysis. Conclusion: Based on the present data, TDT placement can reduce the rate of AL following LAR using the double stapling technique for rectal cancer.

Automated summary

This study retrospectively analyzed data from 556 patients with rectal cancer and found that the placement of a transanal drainage tube (TDT) can reduce the occurrence of anastomotic leakage (AL) following low anterior resection (LAR). Logistic analysis identified the non-use of a TDT as a risk factor for AL.