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1,2,3-Triazole hybrids as anticancer agents: A review

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ARCHIV DER PHARMAZIE
卷 355, 期 1, 页码 -

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WILEY-V C H VERLAG GMBH
DOI: 10.1002/ardp.202100158

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1; 2; 3-triazole; cancer; mechanism of action; structure-activity relationship

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Recent advancements in 1,2,3-triazole hybrids have shown promising potential in the development of anticancer agents. These compounds exhibit remarkable biological potential and offer significant opportunities in combating cancer.
Despite the advancements in the development of anticancer agents, more effective and safer anticancer drugs still need to be developed as the current agents cause unwanted side effects and many patients have become drug resistant. 1,2,3-Triazoles, due to their remarkable biological potential, have received considerable attention in drug discovery for the development of anticancer agents. The present review article presents an overview of the recent advances in 1,2,3-triazole hybrids with anticancer potential over the last 2 years, their chemical structures, structure-activity relationships, and mechanisms of action, as well as insights into the docking studies.

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