期刊
AQUACULTURE
卷 544, 期 -, 页码 -出版社
ELSEVIER
DOI: 10.1016/j.aquaculture.2021.737050
关键词
Bacterial communities; Fish health; Intestinal microbiota; Microbiota modulation; Therapeutic approaches
The intestinal microbiota plays a key role in fish health, affecting growth, mortality, and physiological functions. Therapeutic modulation strategies, including probiotics and prebiotics, can help alleviate dysbiosis and maintain a healthy gut microbiota in fish.
The intestinal epithelium of fish is the major absorptive barrier for nutrients assisted by a large number of microbes. These are known as resident microbiota or gut microbiota, which has a symbiotic relationship with the host, playing key roles in pathogen protection, nutritional, endocrine, neural, and physiological functions. Dysbiosis is an impairment in the balance of the commensal communities forming the gut microbiota. This imbalance is caused by several factors with physiological consequences for the host and subsequent reduced growth and higher mortality rates. Therapeutic modulation strategies of the gut microbiota have been successfully used in higher vertebrate models; however, these procedures can also be adapted for their application to fish and other aquatic animals. Strategies such as probiotics, prebiotics, synbiotics, paraprobiotics, and postbiotics, as well as other emerging strategies, are discussed as potential therapeutic approaches for treating or avoiding dysbiosis in fish.
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