期刊
APPLIED OPTICS
卷 60, 期 31, 页码 9951-9956出版社
OPTICAL SOC AMER
DOI: 10.1364/AO.428048
关键词
-
类别
资金
- Office National d'etudes et de Recherches Aerospatiales (PRF TELEMAC)
- Agence Nationale de la Recherche [ANR-15-RHUS-0001, ANR-18-CE19-0010]
- Agence Nationale de la Recherche (ANR) [ANR-15-RHUS-0001] Funding Source: Agence Nationale de la Recherche (ANR)
The new imaging modality presented in the study offers a range of image contrast from full-field to confocal contrast, depending on the pattern size, providing various trade-offs in terms of contrast and acquisition speed. This allows users to choose the most efficient system for a specific clinical application.
Effective and accurate in vivo diagnosis of retinal pathologies requires high performance imaging devices, combining a large field of view and the ability to discriminate the ballistic signal from the diffuse background in order to provide a highly contrasted image of the retinal structures. Here, we have implemented the partial-field illumination ophthalmoscope, a patterned illumination modality, integrated to a high pixel rate adaptive optics full-field microscope. This non-invasive technique enables us to mitigate the low signal-to-noise ratio, intrinsic of full-field ophthalmoscopes, by partially illuminating the retina with complementary patterns to reconstruct a wide-field image. This new, to the best of our knowledge, modality provides an image contrast spanning from the full-field to the confocal contrast, depending on the pattern size. As a result, it offers various trade-offs in terms of contrast and acquisition speed, guiding the users towards the most efficient system for a particular clinical application. (C) 2021 Optical Society of America
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据