4.7 Article

Genome Analysis of Klebsiella oxytoca Complex for Antimicrobial Resistance and Virulence Genes

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出版社

AMER SOC MICROBIOLOGY
DOI: 10.1128/aac.02183-21

关键词

resistance; Klebsiella oxytoca; virulence; taxonomy; Klebsiella; antimicrobial resistance

资金

  1. National Natural Science Foundation of China [81861138055]
  2. West China Hospital of Sichuan University (1.3.5 project for disciplines of excellence) [ZYYC08006]

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The Klebsiella oxytoca complex consists of nine closely related species that cause human infections, with K. oxytoca and Klebsiella michiganensis being more commonly associated with human infections and carrying more virulence genes.
Klebsiella oxytoca complex comprises nine closely related species causing human infections. We curated genomes labeled Klebsiella (n = 14,256) in GenBank and identified 588 belonging to the complex, which were examined for precise species, sequence types, K- and O-antigen types, and virulence and antimicrobial resistance genes. Klebsiella oxytoca complex comprises nine closely related species causing human infections. We curated genomes labeled Klebsiella (n = 14,256) in GenBank and identified 588 belonging to the complex, which were examined for precise species, sequence types, K- and O-antigen types, and virulence and antimicrobial resistance genes. The complex and Klebsiella pneumoniae share many K- and O-antigen types. Of the complex, K. oxytoca and Klebsiella michiganensis appear to carry more virulence genes and be more commonly associated with human infections.

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