期刊
ANNALS OF THORACIC SURGERY
卷 114, 期 5, 页码 1578-1585出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.athoracsur.2021.09.078
关键词
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资金
- Terumo Aortic
- Jimmy and Roberta Howell Professorship in Cardiovascular Surgery at Baylor College of Medicine
- Cullen Foundation
Staged repair of extensive aortic aneurysms using the elephant trunk technique is associated with significant morbidity and mortality. Patients with acute symptoms are at higher risk of operative death and adverse events.
BACKGROUND Staged open repair of extensive aortic aneurysms by using the elephant trunk (ET) technique has facilitated the treatment of aortic aneurysms that affect the entire thoracic aorta. We describe our nearly 3-decade experience with classic ET repairs. METHODS From 1990 through 2021, we performed 363 stage 1 ET repairs to replace the transverse aortic arch in patients with a median age of 65 years (interquartile range, 56-71 years). Fifty-six patients (15.4%) presented with acute symptoms, and 182 (50.1%) underwent redo sternotomy. After a median interval of 3.2 months (interquartile range, 2.07.3 months), 203 patients (55.9%) underwent stage 2 ET completion; of these, 16 (7.9%) had acute symptoms. Stage 2 repairs comprised 162 (80.6%) extent I or II thoracoabdominal aortic replacements. We examined postoperative outcomes, including operative death, adverse event (a composite end point), survival, and repair failure. RESULTS Operative mortality was 12.4% (45 of 363) after stage 1 and 10.3% (21 of 203) after stage 2. The rates of adverse event were 18.5% (67 of 363) for stage 1 and 18.4% (38 of 203) for stage 2. Acute symptoms independently predicted operative death and adverse events for both stage 1 and stage 2 repairs; additional predictors for stage 2 repairs were older age and extent II repair. Survival was significantly worse for patients who did not receive their stage 2 completion repair than for those who did (P <.001). CONCLUSIONS Treating extensive aortic aneurysms by using the ET technique for staged repair is associated with substantial morbidity and mortality. Patients who present with acute symptoms are at greater risk of operative death and adverse events. Diligent surveillance is needed between stages.
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