4.8 Article

Electrochemical Desaturative β-Acylation of Cyclic N-Aryl Amines

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Electrochemical 1,2-Diarylation of Alkenes Enabled by Direct Dual C-H Functionalizations of Electron-Rich Aromatic Hydrocarbons

Jing-Hao Qin et al.

Summary: This study describes a cobalt-promoted electrochemical method for 1,2-diarylation of alkenes with electron-rich aromatic hydrocarbons, producing polyaryl-functionalized alkanes. Utilizing a radical relay strategy, the chemoselectivity is shifted to dehydrogenative [2+2+2] cycloaddition via 1,2-diarylation by using a graphite rod cathode, resulting in the formation of complex 11,12-dihydroindolo[2,3-a]carbazoles.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Multidisciplinary

Electrochemical Oxidation Induced Selective C-C Bond Cleavage

Shi-Hui Shi et al.

Summary: Selective C-C bond cleavage using electrochemical methods has been identified as a sustainable and scalable strategy that shows potential in replacing chemical reagents with electricity. Progress in this area has been made, with more examples of C-C bond cleavage via different maneuvers being developed recently, showcasing the exciting potential of electrochemical synthesis.

CHEMICAL REVIEWS (2021)

Article Chemistry, Organic

C-H Bond Functionalization of Amines: A Graphical Overview of Diverse Methods

Subhradeep Dutta et al.

Summary: This review provides a concise overview of the methods that enable the functionalization of sp(3) C-H bonds in amines and their derivatives.

SYNOPEN (2021)

Article Chemistry, Physical

Electrochemically induced nickel catalysis for oxygenation reactions with water

Yujie Liang et al.

Summary: This study introduces an electrocatalytic method for oxidation reactions using simple Ni(II)-bipyridine complexes, with water as the oxygen source. The electrochemical process generates active Ni(II)-peroxo species and O-2 for subsequent oxygenation reactions. This strategy may inspire the development of efficient nickel-catalyzed aerobic oxygenations and the exploration of transition-metal-based oxidation chemistry combined with electrochemistry.

NATURE CATALYSIS (2021)

Article Chemistry, Multidisciplinary

Electrochemical Radical Silyl-Oxygenation of Activated Alkenes

Jie Ke et al.

Summary: An efficient electrochemical radical silyl-oxygenation method has been demonstrated for electron-deficient alkenes, providing access to a variety of highly functionalized silicon-containing molecules. The process shows good yields, excellent chemo- and regio-selectivity, and wide substrate scope with high functional-group tolerance, without the need for transition metal catalysts or chemical oxidants. The ability to generate silyl radicals through electrochemical Si-H activation offers new opportunities for the sustainable and green synthesis of valuable organosilicon compounds.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Site-Selective Acceptorless Dehydrogenation of Aliphatics Enabled by Organophotoredox/Cobalt Dual Catalysis

Min-Jie Zhou et al.

Summary: The visible-light-driven, dual-catalyst system described in the study allows for room-temperature, acceptorless-CDA of aliphatics, providing a simple and efficient method for direct dehydrogenation of chemical feedstocks into functionalized olefins. The system demonstrates exceptional site selectivity and functional group tolerance, as well as the ability to synthesize biologically relevant molecules and pharmaceutical ingredients through late-stage dehydrogenation.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Enantioselective Synthesis of N-Alkylamines through β-Amino C-H Functionalization Promoted by Cooperative Actions of B(C6F5)3 and a Chiral Lewis Acid Co-Catalyst

Yejin Chang et al.

Summary: This study presents a catalytic method for beta-C(sp(3))-H functionalization of N-alkylamines to synthesize enantiomerically enriched beta-substituted amines. By using a catalyst system comprising seemingly competitive Lewis acids and chiral metal-based complexes, a variety of delta-amino carbonyl compounds were efficiently synthesized, demonstrating the potential application of the method in synthesizing pharmaceutical compounds and chiral catalysts. Investigations into the mechanistic nuances of the catalytic processes were also described.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Electrochemically Enabled, Nickel-Catalyzed Dehydroxylative Cross-Coupling of Alcohols with Aryl Halides

Zijian Li et al.

Summary: This method utilizes alcohols and aryl bromides as coupling partners, combining anodic preparation and nickel catalysis to efficiently construct C(sp(2))-C(sp(3)) bonds. The nickel-catalyzed paired electrolysis reaction showcases a broad substrate scope suitable for the synthesis of multifunctional compounds.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Multidisciplinary Sciences

Merging shuttle reactions and paired electrolysis for reversible vicinal dihalogenations

Xichang Dong et al.

Summary: The study presents an electrochemically assisted shuttle (e-shuttle) paradigm for the facile and scalable interconversion of alkenes and vicinal dihalides, which can be used to synthesize dihalogenated molecules or recycle waste materials. The method demonstrates dibromination or dichlorination of alkenes using simple setup with inexpensive graphite electrodes. Additionally, it shows the complete dechlorination of hexachlorinated lindane to benzene using simple alkene acceptors in soil samples.

SCIENCE (2021)

Article Multidisciplinary Sciences

Electrophotocatalytic diamination of vicinal C-H bonds

Tao Shen et al.

Summary: In this study, alkylated arenes underwent vicinal C-H diamination reactions through an electrophotocatalytic strategy, forming 1,2-diamine derivatives. The reaction was catalyzed by a trisaminocyclopropenium (TAC) ion, generating stable radical dications and resulting in either 3,4-dihydroimidazole or aziridine products depending on the electrolyte used.

SCIENCE (2021)

Article Multidisciplinary Sciences

Divergent rhodium-catalyzed electrochemical vinylic C-H annulation of acrylamides with alkynes

Yi-Kang Xing et al.

Summary: Alpha-pyridones and alpha-pyrones are common structural motifs in natural products and biologically active compounds. This study reports an oxidant-free Rh-catalyzed electrochemical vinylic C-H annulation of acrylamides with alkynes, providing alpha-pyridones and cyclic imidates through divergent pathways with excellent regioselectivities.

NATURE COMMUNICATIONS (2021)

Article Chemistry, Physical

β-Functionalization of Saturated Aza-Heterocycles Enabled by Organic Photoredox Catalysis

Natalie Holmberg-Douglas et al.

Summary: The direct beta-functionalization of saturated aza-heterocycles has been a challenge due to the nature of beta-C-H bonds. The study demonstrates a successful beta-functionalization approach enabled by a two-step organic photoredox catalysis method, involving copper-mediated dehydrogenation followed by hydrofunctionalization of ene-carbamates. The reaction provides a range of C-C, C-O, and C-N aza-heterocycles at the beta-position.

ACS CATALYSIS (2021)

Article Chemistry, Multidisciplinary

Organic Electrochemistry: Molecular Syntheses with Potential

Cuiju Zhu et al.

Summary: Organic electrosynthesis has emerged as a sustainable platform for molecular assembly, showcasing exceptional selectivities, synergies with photocatalysis or dual electrocatalysis, and novel mechanisms in metallaelectrocatalysis.

ACS CENTRAL SCIENCE (2021)

Article Chemistry, Multidisciplinary

Electrophotocatalytic Acetoxyhydroxylation of Aryl Olefins

He Huang et al.

Summary: A method for acetoxyhydroxylation of olefins with syn stereoselectivity under electrophotocatalytic conditions using a TAC ion catalyst has been developed. The reaction, catalyzed by visible light irradiation at controlled electrochemical potential, converts aryl olefins to glycol monoesters with high chemo- and diastereoselectivity. It can be carried out in batch or flow, enabling the synthesis of multigram quantities of the monoester products.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

N-Ammonium Ylide Mediators for Electrochemical C-H Oxidation

Masato Saito et al.

Summary: This translation discusses the importance of site-specific C-H bond oxidation in organic synthesis and the current limitations of chemical reagents in achieving this transformation. It introduces a platform using N-ammonium ylides as oxidants for site-specific, chemoselective C-H oxidation, which is guided by computation and can be applied to real-world problems in the agricultural and pharmaceutical sectors.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

Electrochemically driven desaturation of carbonyl compounds

Samer Gnaim et al.

Summary: This new electrochemical method utilizes electrons as the primary reagent to efficiently achieve carbonyl desaturation from enol silanes and phosphates, demonstrating a broad scope of applicability and scalability.

NATURE CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Chemoselective, Scalable Nickel-Electrocatalytic O-Arylation of Alcohols

Hai-Jun Zhang et al.

Summary: The formation of aryl-alkyl ether bonds through cross coupling of alcohols with aryl halides using a Ni-catalyzed electrochemical method is a useful and operationally simple strategy with a broad substrate scope. This method does not require strong base or expensive transition metal catalysts, and can be easily scaled up in batch or flow settings. Additionally, e-etherification shows an enhanced substrate scope compared to the mechanistically related photochemical variant.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Article Chemistry, Multidisciplinary

Direct Synthesis of Enamides via Electrophilic Activation of Amides

Philipp Spiess et al.

Summary: This study reports a novel and simple reaction for the one-step N-dehydrogenation of amides to enamides, using the unlikely combination of LiHMDS and triflic anhydride. The formed enamides demonstrate broad substrate scope and synthetic utility in downstream transformations.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

TEMPO-Enabled Electrochemical Enantioselective Oxidative Coupling of Secondary Acyclic Amines with Ketones

Zhen-Hua Wang et al.

Summary: An electrochemical asymmetric coupling of secondary acyclic amines with ketones via Shono-type oxidation was achieved, resulting in good to excellent diastereoselectivity and enantioselectivity of the corresponding amino acid derivatives. The addition of an N-oxyl radical as a redox mediator allowed for selective oxidation of the substrate over the product, maintaining reaction selectivity.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Article Chemistry, Multidisciplinary

C-H Amination via Electrophotocatalytic Ritter-type Reaction

Tao Shen et al.

Summary: A method for C-H bond amination via electrophotocatalytic Ritter-type reaction has been developed, catalyzed by a trisaminocyclopropenium (TAC) ion in an electrochemical cell under irradiation, converting benzylic C-H bonds to acetamides without stoichiometric chemical oxidant. The method demonstrates compatibility with a wide range of functionalities and shows successful transformation of several complex substrates.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2021)

Review Chemistry, Organic

Condensation-Based Methods for the C-H Bond Functionalization of Amines

Weijie Chen et al.

Summary: This review provides a comprehensive overview of condensation-based methods for C-H bond functionalization of amines using azomethine ylides as key intermediates, which allow rapid transformation of simple starting materials into complex amines.

SYNTHESIS-STUTTGART (2021)

Review Multidisciplinary Sciences

Recent advances in organic electrosynthesis employing transition metal complexes as electrocatalysts

Cong Ma et al.

Summary: Organic electrosynthesis utilizes electric current as a traceless redox agent, providing an environmentally conscious alternative; indirect electrolysis with redox catalysts can avoid overpotential of electron transfer, achieving wide functional group tolerance and selectivity control.

SCIENCE BULLETIN (2021)

Review Chemistry, Multidisciplinary

Late-stage C-H functionalization offers new opportunities in drug discovery

Lucas Guillemard et al.

Summary: In the past decade, the introduction of late-stage functionalization methodologies has significantly advanced the landscape of molecular synthesis. Particularly, C-H functionalization approaches have led to improvements in resource economy and new strategies for drug discovery. However, challenges and limitations in current LSF methods indicate the need for future improvements and development of new approaches.

NATURE REVIEWS CHEMISTRY (2021)

Article Chemistry, Multidisciplinary

Rhodaelectro-Catalyzed C-H and C-C Activation

Youai Qiu et al.

Summary: Rhodium(III) catalysis has been crucial in advancing oxidative C-H functionalizations in the last decade, although it has mainly relied on stoichiometric amounts of toxic and expensive metal oxidants like silver(I) salts. The emerging field of electrosynthesis is seen as a promising alternative to these toxic and expensive oxidants, with recent progress merging electrocatalysis with organometallic C-H activation. However, developing user-friendly and robust rhodaelectro-catalysis for oxidative C-H activations has been challenging until very recently.

CCS CHEMISTRY (2021)

Review Chemistry, Multidisciplinary

Green chemistry meets medicinal chemistry: a perspective on modern metal-free late-stage functionalization reactions

Juan D. Lasso et al.

Summary: The progress of drug discovery and development is greatly influenced by milestones reached in organic synthesis, particularly the recent breakthrough in late-stage functionalization (LSF) reactions. The presence of metals in traditional organometallic methods poses drawbacks in terms of cost, environmental hazard, and health risks, leading to the development of metal-free LSF methodologies guided by green chemistry directives. The review expands the discussion on metal-free LSF reactions by exploring various forms of transformations and discussing specific challenges, solutions, and future research opportunities in the field.

CHEMICAL SOCIETY REVIEWS (2021)

Review Chemistry, Organic

Recent advances in the functionalization of saturated cyclic amines

Yan He et al.

Summary: In recent decades, efforts have been made for the development of more efficient and sustainable methods for the functionalization of saturated cyclic amines, as simple cyclic amines are readily available with low cost and functionalized cyclic amines are highly valuable in synthetic and biological applications.

ORGANIC CHEMISTRY FRONTIERS (2021)

Review Chemistry, Multidisciplinary

Electrocatalysis as an enabling technology for organic synthesis

Luiz F. T. Novaes et al.

Summary: Electrochemistry has recently become a versatile strategy in achieving challenging transformations in synthetic organic chemistry. The use of redox-active electrocatalysts has increased in recent developments in electrosynthesis to enhance control over reactive intermediates. Electrocatalytic mediators allow for synthetic transformations to proceed in a manner different from purely chemical methods.

CHEMICAL SOCIETY REVIEWS (2021)

Review Chemistry, Multidisciplinary

Visible light photocatalysis in the late-stage functionalization of pharmaceutically relevant compounds

Rolando Cannalire et al.

Summary: Late stage functionalization is a powerful tool for accelerating the identification of structure-activity relationships and optimizing ADME profiles of drugs. Visible-light photocatalysis offers a smooth and clean functionalization approach for drugs, with a critical assessment of current literature and highlighting expected future progress and potential applications in the field.

CHEMICAL SOCIETY REVIEWS (2021)

Article Chemistry, Organic

Transition-Metal-Free Functionalization of Saturated and Unsaturated Amines to Bioactive Alkaloids Mediated by Sodium Chlorite

Julio Romero-Ibanez et al.

Summary: New approaches to alkaloid synthesis through the functionalization of C(sp(3))-H and C(sp(2))=C(sp(2)) bonds of simple N-heterocycles have been highlighted. The use of NaClO2 as an alternative to transition-metal catalysts allows for the synthesis of bioactive alkaloids in an economically and ecologically friendly manner. This method reduces unwanted metal waste and produces harmless NaCl waste.

SYNLETT (2021)

Article Chemistry, Multidisciplinary

Dialling-In New Reactivity into the Shono-type Anodic Oxidation Reaction

Alan M. Jones

Summary: This study describes the author's research on electrosynthetic anodic oxidation, focusing on the discovery of the Oxa-Shono reaction and its applications in selective oxidation and de-esterification processes. This bio-inspired advance in dealkylation chemistry provides exquisite control over reaction outcomes and mimics metabolic processes observed in nature.

CHEMICAL RECORD (2021)

Article Chemistry, Multidisciplinary

Dehydrogenative Anodic C-C Coupling of Phenols Bearing Electron-Withdrawing Groups

Johannes L. Roeckl et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Review Chemistry, Multidisciplinary

Metalla-electrocatalyzed C-H Activation by Earth-Abundant 3d Metals and Beyond

Lutz Ackermann

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Review Chemistry, Multidisciplinary

A Decade of Electrochemical Dehydrogenative C,C-Coupling of Aryls

Johannes L. Roeckl et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Review Chemistry, Multidisciplinary

Anodic Oxidation for the Stereoselective Synthesis of Heterocycles

Kosuke Yamamoto et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Review Chemistry, Multidisciplinary

A Survival Guide for the Electro-curious

Cian Kingston et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Review Chemistry, Multidisciplinary

Site-Selective C-H Functionalization via Synergistic Use of Electrochemistry and Transition Metal Catalysis

Ke-Jin Jiao et al.

ACCOUNTS OF CHEMICAL RESEARCH (2020)

Article Chemistry, Multidisciplinary

Azaruthena(II)-bicyclo[3.2.0]heptadiene: Key Intermediate for Ruthenaelectro(II/III/I)-catalyzed Alkyne Annulations

Long Yang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Cobalt-Catalyzed Asymmetric Hydrogenation of alpha,beta-Unsaturated Carboxylic Acids by Homolytic H-2 Cleavage

Hongyu Zhong et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Multidisciplinary Sciences

Site-selective electrooxidation of methylarenes to aromatic acetals

Peng Xiong et al.

NATURE COMMUNICATIONS (2020)

Article Chemistry, Organic

Electrochemical Ruthenium-Catalyzed C-H Hydroxylation of Amine Derivatives in Aqueous Acid

Sophia G. Robinson et al.

ORGANIC LETTERS (2020)

Article Chemistry, Multidisciplinary

Catalytic Asymmetric Electrochemical α-Arylation of Cyclic β-Ketocarbonyls with Anodic Benzyne Intermediates

Longji Li et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Dual electrocatalysis enables enantioselective hydrocyanation of conjugated alkenes

Lu Song et al.

NATURE CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Electron-Rich Phenoxyl Mediators Improve Thermodynamic Performance of Electrocatalytic Alcohol Oxidation with an Iridium Pincer Complex

Conor M. Galvin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2020)

Article Chemistry, Multidisciplinary

Nickel-Catalyzed Thiolation of Aryl Halides and Heteroaryl Halides through Electrochemistry

Dong Liu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications

Yu Kawamata et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Chemistry, Multidisciplinary

Anodic Cyclizations, Seven-Membered Rings, and the Choice of Radical Cation vs. Radical Pathways

Robert J. Perkins et al.

CHINESE JOURNAL OF CHEMISTRY (2019)

Article Chemistry, Multidisciplinary

New Bisoxazoline Ligands Enable Enantioselective Electrocatalytic Cyanofunctionalization of Vinylarenes

Niankai Fu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)

Article Multidisciplinary Sciences

Hindered dialkyl ether synthesis with electrogenerated carbocations

Jinbao Xiang et al.

NATURE (2019)

Article Chemistry, Physical

Manganese-Catalyzed Desaturation of N-Acyl Amines and Ethers

Gang Li et al.

ACS CATALYSIS (2019)

Review Chemistry, Multidisciplinary

Electrochemical Oxidative Cross-Coupling with Hydrogen Evolution Reactions

Yong Yuan et al.

ACCOUNTS OF CHEMICAL RESEARCH (2019)

Article Chemistry, Multidisciplinary

Facilitating Gold Redox Catalysis with Electrochemistry: An Efficient Chemical-Oxidant-Free Approach

Xiaohan Ye et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Scalable Rhodium(III)-Catalyzed Aryl C-H Phosphorylation Enabled by Anodic Oxidation Induced Reductive Elimination

Zheng-Jian Wu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Multidisciplinary Sciences

Practical and stereoselective electrocatalytic 1,2-diamination of alkenes

Chen-Yan Cai et al.

NATURE COMMUNICATIONS (2019)

Article Chemistry, Multidisciplinary

Efficient Electrocatalysis for the Preparation of (Hetero)aryl Chlorides and Vinyl Chloride with 1,2-Dichloroethane

Yujie Liang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Electro-Oxidative S-H/S-H Cross-Coupling with Hydrogen Evolution: Facile Access to Unsymmetrical Disulfides

Pengfei Huang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Review Chemistry, Multidisciplinary

Late-Stage Peptide Diversification by Position-Selective C-H Activation

Wei Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Electrooxidative Ruthenium-Catalyzed C-H/O-H Annulation by Weak O-Coordination

Youai Qiu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Electrochemical Functional-Group-Tolerant Shono-type Oxidation of Cyclic Carbamates Enabled by Aminoxyl Mediators

Fei Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Review Chemistry, Multidisciplinary

Electrochemical Arylation Reaction

Siegfried R. Waldvogel et al.

CHEMICAL REVIEWS (2018)

Review Chemistry, Multidisciplinary

Electrochemical strategies for C-H functionalization and C-N bond formation

Markus D. Karkas

CHEMICAL SOCIETY REVIEWS (2018)

Article Chemistry, Multidisciplinary

Transfer Hydrogenation of Alkenes Using Ethanol Catalyzed by a NCP Pincer Iridium Complex: Scope and Mechanism

Yulei Wang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Cobalt(II)-Catalyzed Electrooxidative C-H Amination of Arenes with Alkylamines

Xinlong Gao et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

General, Mild, and Selective Method for Desaturation of Aliphatic Amines

Padon Chuentragool et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Electrochemical Difluoromethylarylation of Alkynes

Peng Xiong et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Review Chemistry, Organic

Recent advances in iodine mediated electrochemical oxidative cross-coupling

Kun Liu et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2018)

Article Chemistry, Multidisciplinary

Oxidative β-C-H sulfonylation of cyclic amines

R. J. Griffiths et al.

CHEMICAL SCIENCE (2018)

Review Chemistry, Physical

Electrocatalytic C-H Activation

Nicolas Sauermann et al.

ACS CATALYSIS (2018)

Article Chemistry, Multidisciplinary

Cathode Material Determines Product Selectivity for Electrochemical C-H Functionalization of Biaryl Ketoximes

Huai-Bo Zhao et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Iridium-Catalyzed Electrooxidative C-H Activation by Chemoselective Redox-Catalyst Cooperation

Youai Qiu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)

Article Chemistry, Multidisciplinary

Copper-Catalyzed Electrochemical C-H Amination of Arenes with Secondary Amines

Qi-Liang Yang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Multidisciplinary Sciences

Dehydrogenative reagent-free annulation of alkenes with diols for the synthesis of saturated O-heterocycles

Chen-Yan Cai et al.

NATURE COMMUNICATIONS (2018)

Article Chemistry, Multidisciplinary

Electrochemical Cobalt-Catalyzed C-H Oxygenation at Room Temperature

Nicolas Sauermann et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Chemistry, Multidisciplinary

Electrocatalytic Radical Dichlorination of Alkenes with Nucleophilic Chlorine Sources

Niankai Fu et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Chemistry, Multidisciplinary

Scalable, Electrochemical Oxidation of Unactivated C-H Bonds

Yu Kawamata et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Chemistry, Multidisciplinary

Palladium-Catalyzed C(sp3)-H Oxygenation via Electrochemical Oxidation

Qi-Liang Yang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Article Multidisciplinary Sciences

Metal-catalyzed electrochemical diazidation of alkenes

Niankai Fu et al.

SCIENCE (2017)

Review Chemistry, Multidisciplinary

Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance

Ming Yan et al.

CHEMICAL REVIEWS (2017)

Article Chemistry, Multidisciplinary

Copper-catalyzed Mannich-type oxidative β-functionalization of tertiary amines

Min-Jie Zhou et al.

CHEMICAL COMMUNICATIONS (2017)

Article Chemistry, Multidisciplinary

Synthesis of C3-Fluorinated Oxindoles through Reagent-Free Cross-Dehydrogenative Coupling

Zheng-Jian Wu et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Reagent- and Metal-Free Anodic C-C Cross-Coupling of Aniline Derivatives

Lara Schulz et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Article Chemistry, Multidisciplinary

Electrocatalytic Oxidant-Free Dehydrogenative C-H/S-H Cross-Coupling

Pan Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)

Editorial Material Chemistry, Multidisciplinary

Electrochemical Allylic Oxidation of Olefins: Sustainable and Safe

Siegfried R. Waldvogel et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Chemistry, Multidisciplinary

N-Heterocyclic Carbene Ligand-Enabled C(sp3)-H Arylation of Piperidine and Tetrahydropyran Derivatives

Shengqing Ye et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

Article Multidisciplinary Sciences

Cooperative electrocatalytic alcohol oxidation with electron-proton-transfer mediators

Artavazd Badalyan et al.

NATURE (2016)

Article Multidisciplinary Sciences

Scalable and sustainable electrochemical allylic C-H oxidation

Evan J. Horn et al.

NATURE (2016)

Review Chemistry, Multidisciplinary

Iron- and Cobalt-Catalyzed Alkene Hydrogenation: Catalysis with Both Redox-Active and Strong Field Ligands

Paul J. Chirik

ACCOUNTS OF CHEMICAL RESEARCH (2015)

Review Chemistry, Multidisciplinary

Amine Functionalization via Oxidative Photoredox Catalysis: Methodology Development and Complex Molecule Synthesis

Joel W. Beatty et al.

ACCOUNTS OF CHEMICAL RESEARCH (2015)

Article Chemistry, Multidisciplinary

Radical C-H Functionalization of Heteroarenes under Electrochemical Control

Alexander G. O'Brien et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Multidisciplinary

Metal- and Reagent-Free Highly Selective Anodic Cross-Coupling Reaction of Phenols

Bernd Elsler et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)

Article Chemistry, Organic

Synthesis of Saturated N-Heterocycles

Cam-Van T. Vo et al.

JOURNAL OF ORGANIC CHEMISTRY (2014)

Article Chemistry, Multidisciplinary

Bis(phosphine)cobalt Dialkyl Complexes for Directed Catalytic Alkene Hydrogenation

Max R. Friedfeld et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2014)

Article Chemistry, Multidisciplinary

C-H bond activation enables the rapid construction and late-stage diversification of functional molecules

Joanna Wencel-Delord et al.

NATURE CHEMISTRY (2013)

Article Chemistry, Organic

Iron-Catalyzed Oxidative C(3)-H Functionalization of Amines

Noriaki Takasu et al.

ORGANIC LETTERS (2013)

Article Chemistry, Multidisciplinary

Ligand-controlled β-selective C(sp3)-H arylation of N-Boc-piperidines

Anthony Millet et al.

CHEMICAL SCIENCE (2013)

Review Chemistry, Multidisciplinary

C-H Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

Junichiro Yamaguchi et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)

Review Chemistry, Multidisciplinary

Direct α-Functionalization of Saturated Cyclic Amines

Emily A. Mitchell et al.

CHEMISTRY-A EUROPEAN JOURNAL (2012)

Review Chemistry, Multidisciplinary

Transition Metal-Catalyzed Enantioselective Hydrogenation of Enamines and Imines

Jian-Hua Xie et al.

CHEMICAL REVIEWS (2011)

Article Chemistry, Multidisciplinary

sp3 C-H Bond Activation with Ruthenium(II) Catalysts and C(3)-Alkylation of Cyclic Amines

Basker Sundararaju et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)

Article Chemistry, Multidisciplinary

Anodic Phenol-Arene Cross-Coupling Reaction on Boron-Doped Diamond Electrodes

Axel Kirste et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)

Article Chemistry, Multidisciplinary

Palladium-Catalyzed Aromatic C-H Halogenation with Hydrogen Halides by Means of Electrochemical Oxidation

Fumitoshi Kakiuchi et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)

Review Chemistry, Multidisciplinary

Contribution of electrochemistry to organometallic catalysis

Anny Jutand

CHEMICAL REVIEWS (2008)

Review Chemistry, Multidisciplinary

Modern strategies in electroorganic synthesis

Jun-ichi Yoshida et al.

CHEMICAL REVIEWS (2008)

Review Chemistry, Multidisciplinary

Asymmetric enamine catalysis

Santanu Mukherjee et al.

CHEMICAL REVIEWS (2007)

Review Multidisciplinary Sciences

C-H bond functionalization in complex organic synthesis

K Godula et al.

SCIENCE (2006)

Article Chemistry, Multidisciplinary

Novel synthesis of enamines by iridium-catalyzed dehydrogenation of tertiary amines

XW Zhang et al.

CHEMICAL COMMUNICATIONS (2003)