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Newborns' passive humoral SARS-CoV-2 immunity following heterologous vaccination of the mother during pregnancy

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2022)

Severe acute respiratory syndrome coronavirus 2 serology levels in pregnant women and their neonates

Jeffrey M. Kubiak et al.

Summary: This study examined the serologic response in pregnant women to SARS-CoV-2 and explored its correlation with maternal clinical presentation as well as the passive immunity received by neonates. The results showed that maternal serologies were correlated with symptomatic maternal infection, and higher levels of maternal antibodies were associated with passive neonatal immunity.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2021)

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Article Obstetrics & Gynecology

Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study

Kathryn J. Gray et al.

Summary: The study found that pregnant and lactating women had equivalent antibody titers after receiving the coronavirus disease 2019 mRNA vaccine compared to nonpregnant women, and these titers were higher than those induced by natural infection. Vaccine-induced antibodies were present in umbilical cord blood and breastmilk samples, transferring immunity to neonates through placenta and breastmilk.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2021)

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Editorial Material Obstetrics & Gynecology

Cord blood antibodies following maternal coronavirus disease 2019 vaccination during pregnancy

Leena B. Mithal et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2021)

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Article Medicine, General & Internal

Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial

Xinxue Liu et al.

Summary: Heterologous prime-boost COVID-19 vaccine schedules could facilitate mass immunisation, with ChAd/BNT showing non-inferior immunogenicity compared to ChAd/ChAd, but BNT/ChAd did not demonstrate non-inferiority to BNT/BNT. The results support flexibility in using heterologous prime-boost vaccination with ChAd and BNT COVID-19 vaccines.

LANCET (2021)

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Newborns' passive humoral SARS-CoV-2 immunity following heterologous vaccination of the mother during pregnancy

相关参考文献

Severe acute respiratory syndrome coronavirus 2 serology levels in pregnant women and their neonates

Coronavirus disease 2019 vaccine response in pregnant and lactating women: a cohort study

Cord blood antibodies following maternal coronavirus disease 2019 vaccination during pregnancy

Safety and immunogenicity of heterologous versus homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine (Com-COV): a single-blind, randomised, non-inferiority trial

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