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Pseudo-Central Pontine Myelinolysis

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LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/PAF.0000000000000731

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central pontine myelinolysis; demyelination; hyponatremia; forensic autopsy; Luxol fast blue stain

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This article discusses the importance of appropriate microscopic and immunohistochemical analysis of suspected cases of central pontine myelinolysis.
Central pontine myelinolysis is most commonly associated with rapid correction of hyponatremia and has historically been associated with alcoholism. In this case report, 2 deaths with gross findings of central pontine lesions led to the possibility that CPM may have been a potential mechanism of death. Subsequent analysis revealed that these lesions were incidental findings. This case report discusses the importance of appropriate microscopic and immunohistochemical analysis of suspected CPM cases.

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