期刊
AMERICAN JOURNAL OF CHINESE MEDICINE
卷 50, 期 2, 页码 471-509出版社
WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S0192415X22500185
关键词
Dendrobium Polysaccharides; Structural Characterization; Biological Activities; Structure-Activity Relationships; Industrial Applications; Review
资金
- Beijing Science and Technology Project [Z201100005420005]
This review systematically summarizes the preparation techniques, structural characteristics, pharmacological activities, and current industrial applications of Dendrobium polysaccharides. DPSs have diverse structures and biological activities, with a significant impact on immune enhancement and pharmaceutical and healthcare applications.
Dendrobium polysaccharides (DPSs) have aroused people's increasing attention in recent years as a result of their outstanding edible and medicinal values and non-toxic property. This review systematically summarized recent progress in the different preparation techniques, structural characteristics, modification, various pharmacological activities and molecular mechanisms, structure-activity relationships, and current industrial applications in the medicinal, food, and cosmetics fields of DPSs. Additionally, some recommendations for future investigations were provided. A variety of methods were applied for the extraction and purification of DPSs. They possessed primary structures (e.g., glucomannan, rhamnogalacturonan I type pectin, heteroxylan, and galactoglucan) and conformational structures (e.g., random coil, rod, globular, and a slight triple-helical). And different molecular weights, monosaccharide compositions, linkage types, and modifications could largely affect DPSs' bioactivities (e.g., immunomodulatory, anti-diabetic, hepatoprotective, gastrointestinal protective, antitumor, anti-inflammatory, and anti-oxidant activities). It was worth mentioning that DPSs were significant pharmaceutical remedies and therapeutic supplements especially due to their strong immunity enhancement abilities. We hope that this review will lay a solid foundation for further development and applications of Dendrobium polysaccharides.
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