All-Carbon Tetrasubstituted Olefins Synthesis from Diazo Compounds and Iodonium Ylides under Blue LED Irradiation

A route for the construction of all-carbon tetra-substituted olefins through visible-light promoted coupling of diazo compounds with iodonium ylides was developed. A wide range of all-carbon tetra-substituted olefins was obtained in moderate to good yields. The synthetic values of the current method were further approved by the synthesis of natural isolates modified alkenes and the successful transformation of final olefins into important heterocycles.

Automated summary

A new method for the construction of all-carbon tetra-substituted olefins using visible-light promoted coupling of diazo compounds with iodonium ylides has been developed, resulting in a wide range of products in moderate to good yields. The synthetic value of this method was demonstrated through the synthesis of natural isolates modified alkenes and the successful transformation of final olefins into important heterocycles.