期刊
ADVANCED MATERIALS
卷 34, 期 5, 页码 -出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/adma.202107177
关键词
cell membranes; detoxification; drug delivery; immunotherapy; micromotors; phototherapy
类别
资金
- Defense Threat Reduction Agency Joint Science and Technology Office for Chemical and Biological Defense [HDTRA1-18-1-0014]
- National Science Foundation [DMR-1904702]
Cell membrane-functionalized micromotors have attracted considerable interest for biomedical applications due to their biofunctional, versatile, and adaptive capabilities. This new class of micromotors demonstrates enhanced performance in complex biological environments, showing potential in advancing micromotor research.
There has been considerable interest in developing synthetic micromotors with biofunctional, versatile, and adaptive capabilities for biomedical applications. In this perspective, cell membrane-functionalized micromotors emerge as an attractive platform. This new class of micromotors demonstrates enhanced propulsion and compelling performance in complex biological environments, making them suitable for various in vivo applications, including drug delivery, detoxification, immune modulation, and phototherapy. This article reviews various proof-of-concept studies based on different micromotor designs and cell membrane coatings in these areas. The review focuses on the motor structure and performance relationship and highlights how cell membrane functionalization overcomes the obstacles faced by traditional synthetic micromotors while imparting them with unique capabilities. Overall, the cell membrane-functionalized micromotors are expected to advance micromotor research and facilitate its translation towards practical uses.
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