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BMC MOLECULAR BIOLOGY (2017)
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CANCER LETTERS (2017)
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Jin Shang et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation
Antonio Pisano et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
B Cell-Intrinsic Expression of the HuR RNA-Binding Protein Is Required for the T Cell-Dependent Immune Response In Vivo
Amy DeMicco et al.
JOURNAL OF IMMUNOLOGY (2015)
Rhythmic control of mRNA stability modulates circadian amplitude of mouse Period3 mRNA
Sung-Hoon Kim et al.
JOURNAL OF NEUROCHEMISTRY (2015)
Stimuli-Responsive Nanomaterials for Biomedical Applications
Angela P. Blum et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma
Charlene Vigouroux et al.
LUNG CANCER (2015)
The RNA-binding protein HuR is essential for the B cell antibody response
Manuel D. Diaz-Munoz et al.
NATURE IMMUNOLOGY (2015)
The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers
Jun Qian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Exosomes in bodily fluids are a highly stable resource of disease biomarkers
Stephanie Boukouris et al.
PROTEOMICS CLINICAL APPLICATIONS (2015)
RNA-stabilizing proteins as molecular targets in cardiovascular pathologies
Sahana Suresh Babu et al.
TRENDS IN CARDIOVASCULAR MEDICINE (2015)
HuR mediated post-transcriptional regulation as a new potential adjuvant therapeutic target in chemotherapy for pancreatic cancer
Aldona Jakstaite et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2015)
Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells
Masaya Jimbo et al.
ONCOTARGET (2015)
Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function
Vito Giuseppe D'Agostino et al.
Scientific Reports (2015)
Non-small-cell lung cancer
Cesare Gridelli et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
Reduced PDCD4 Expression Promotes Cell Growth Through PI3K/Akt Signaling in Non-Small Cell Lung Cancer
Yan Zhen et al.
ONCOLOGY RESEARCH (2015)
Hu-antigen receptor (HuR) and cyclooxygenase-2 (COX-2) expression in human non-small-cell lung carcinoma: associations with clinicopathological parameters, tumor proliferative capacity and patients' survival
Constantinos Giaginis et al.
TUMOR BIOLOGY (2015)
Liposomal siRNA nanocarriers for cancer therapy
Bulent Ozpolat et al.
ADVANCED DRUG DELIVERY REVIEWS (2014)
The Critical Role of mRNA Destabilizing Protein Heterogeneous Nuclear Ribonucleoprotein D in 3′ Untranslated Region-Mediated Decay of Low-Density Lipoprotein Receptor mRNA in Liver Tissue
Amar Bahadur Singh et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2014)
Posttranscriptional control of the chemokine receptor CXCR4 expression in cancer cells
Norah Al-Souhibani et al.
CARCINOGENESIS (2014)
High Sam68 expression predicts poor prognosis in non-small cell lung cancer
Z. Zhang et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2014)
A census of human RNA-binding proteins
Stefanie Gerstberger et al.
NATURE REVIEWS GENETICS (2014)
Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs
Je-Hyun Yoon et al.
NUCLEIC ACIDS RESEARCH (2014)
The C-terminal RNA binding motif of HuR is a multi-functional domain leading to HuR oligomerization and binding to U-rich RNA targets
Rafael M. Scheiba et al.
RNA BIOLOGY (2014)
Downregulation of hnRNP K by RNAi inhibits growth of human lung carcinoma cells
Fengming Tang et al.
ONCOLOGY LETTERS (2014)
IMP3 RNP Safe Houses Prevent miRNA-Directed HMGA2 mRNA Decay in Cancer and Development
Lars Jonson et al.
CELL REPORTS (2014)
The RNA-Binding Protein QKI Suppresses Cancer-Associated Aberrant Splicing
Feng-Yang Zong et al.
PLOS GENETICS (2014)
Loss of the multifunctional RNA-binding protein RBM47 as a source of selectable metastatic traits in breast cancer
Sakari Vanharanta et al.
ELIFE (2014)
Dendrimers: synthesis, applications, and properties
Elham Abbasi et al.
NANOSCALE RESEARCH LETTERS (2014)
Domain-specific phosphomimetic mutation allows dissection of different protein kinase C (PKC) isotype-triggered activities of the RNA binding protein HuR
Sebastian Schulz et al.
CELLULAR SIGNALLING (2013)
Molecular Pathways: Adipose Inflammation as a Mediator of Obesity-Associated Cancer
Louise R. Howe et al.
CLINICAL CANCER RESEARCH (2013)
Epithelial cell adhesion molecule-targeted drug delivery for cancer therapy
Manuel Simon et al.
EXPERT OPINION ON DRUG DELIVERY (2013)
Risk of Colorectal High-Grade Dysplasia and Cancer in a Prospective Observational Cohort of Patients With Inflammatory Bowel Disease
Laurent Beaugerie et al.
GASTROENTEROLOGY (2013)
The p97-UBXD8 complex destabilizes mRNA by promoting release of ubiquitinated HuR from mRNP
Hua-Lin Zhou et al.
GENES & DEVELOPMENT (2013)
Multiple Functions of the RNA-Binding Protein HuR in Cancer Progression, Treatment Responses and Prognosis
Jun Wang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Antagonistic Function of the RNA-binding Protein HuR and miR-200b in Post-transcriptional Regulation of Vascular Endothelial Growth Factor-A Expression and Angiogenesis
Sung-Hee Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
MicroRNA-519a demonstrates significant tumour suppressive activity in laryngeal squamous cells by targeting anti-carcinoma HuR gene
Z. Shen et al.
JOURNAL OF LARYNGOLOGY AND OTOLOGY (2013)
The splicing factor SRSF6 is amplified and is an oncoprotein inlung and colon cancers
Michal Cohen-Eliav et al.
JOURNAL OF PATHOLOGY (2013)
Active Stabilization of Human Endothelial Nitric Oxide Synthase mRNA by hnRNP E1 Protects against Antisense RNA and MicroRNAs
J. J. David Ho et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
MPT0B098, a Novel Microtubule Inhibitor That Destabilizes the Hypoxia-Inducible Factor-1α mRNA through Decreasing Nuclear-Cytoplasmic Translocation of RNA-Binding Protein HuR
Yun-Ching Cheng et al.
MOLECULAR CANCER THERAPEUTICS (2013)
A compendium of RNA-binding motifs for decoding gene regulation
Debashish Ray et al.
NATURE (2013)
High Expression of HuR in Cytoplasm, but Not Nuclei, Is Associated with Malignant Aggressiveness and Prognosis in Bladder Cancer
Yasuyoshi Miyata et al.
PLOS ONE (2013)
Arid5a controls IL-6 mRNA stability, which contributes to elevation of IL-6 level in vivo
Kazuya Masuda et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells
Sudha Talwar et al.
RNA BIOLOGY (2013)
Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination
Je-Hyun Yoon et al.
NATURE COMMUNICATIONS (2013)
Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer
Xiao-Yang Wang et al.
ONCOTARGET (2013)
Liposome: classification, preparation, and applications
Abolfazl Akbarzadeh et al.
NANOSCALE RESEARCH LETTERS (2013)
Dendrimers for siRNA Delivery
Swati Biswas et al.
PHARMACEUTICALS (2013)
HuR function in disease
Subramanya Srikantan et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2012)
Murine double minute 2 regulates Hu antigen R stability in human liver and colon cancer through NEDDylation
Nieves Embade et al.
HEPATOLOGY (2012)
Human antigen R contributes to hepatic stellate cell activation and liver fibrosis
Ashwin Woodhoo et al.
HEPATOLOGY (2012)
Differential Expression of RBM5, EGFR and KRAS mRNA and protein in non-small cell lung cancer tissues
Hong Liang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2012)
Heat Shock Transcription Factor Hsf1 Is Involved in Tumor Progression via Regulation of Hypoxia-Inducible Factor 1 and RNA-Binding Protein HuR
Vladimir L. Gabai et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells
Elisa Latorre et al.
MOLECULAR CANCER (2012)
The mRNA Stability Factor HuR Inhibits MicroRNA-16 Targeting of COX-2
Lisa E. Young et al.
MOLECULAR CANCER RESEARCH (2012)
LincRNA-p21 Suppresses Target mRNA Translation
Je-Hyun Yoon et al.
MOLECULAR CELL (2012)
HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium
T. Kurosu et al.
BRITISH JOURNAL OF CANCER (2011)
The RNA-binding Protein HuR Stabilizes Cytosolic Phospholipase A2α mRNA under Interleukin-1β Treatment in Non-small Cell Lung Cancer A549 Cells
Wan-Lin Liao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Expression of HuR, COX-2, and survivin in lung cancers; cytoplasmic HuR stabilizes cyclooxygenase-2 in squamous cell carcinomas
Gou Young Kim et al.
MODERN PATHOLOGY (2011)
A Novel Role of Vimentin Filaments: Binding and Stabilization of Collagen mRNAs
Azariyas A. Challa et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
The RNA-binding protein ELAVL1/HuR is essential for mouse spermatogenesis, acting both at meiotic and postmeiotic stages
Mai Nguyen Chi et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
The RNA-Binding Protein HuR Promotes Glioma Growth and Treatment Resistance
Natalia Filippova et al.
MOLECULAR CANCER RESEARCH (2011)
Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step
George S. Hussey et al.
MOLECULAR CELL (2011)
Cytoplasmic HuR expression correlates with angiogenesis, lymphangiogenesis, and poor outcome in lung cancer
Jun Wang et al.
MEDICAL ONCOLOGY (2011)
Ocular neuroprotection by siRNA targeting caspase-2
Z. Ahmed et al.
CELL DEATH & DISEASE (2011)
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
C. Frank Bennett et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
PCBP1 Suppresses the Translation of Metastasis-Associated PRL-3 Phosphatase
Haihe Wang et al.
CANCER CELL (2010)
Modification at HuR(S242) alters HuR localization and proliferative influence
Hyeon Ho Kim et al.
CELL CYCLE (2010)
Stability Control of MTL1 mRNA by the RNA-Binding Protein Khd1p in Yeast
Naoko Mauchi et al.
CELL STRUCTURE AND FUNCTION (2010)
Tristetraprolin regulates expression of VEGF and tumorigenesis in human colon cancer
Hyun Hee Lee et al.
INTERNATIONAL JOURNAL OF CANCER (2010)
Loss of Repression of HuR Translation by miR-16 May Be Responsible for the Elevation of HuR in Human Breast Carcinoma
Fang Xu et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2010)
Inhibitory effect of HuR gene small interfering RNA segment on laryngeal carcinoma Hep-2 cell growth
Z. Shen et al.
JOURNAL OF LARYNGOLOGY AND OTOLOGY (2010)
Tandem Phosphorylation of Serines 221 and 318 by Protein Kinase Cδ Coordinates mRNA Binding and Nucleocytoplasmic Shuttling of HuR
Anke Doller et al.
MOLECULAR AND CELLULAR BIOLOGY (2010)
The Role of HuR in Gemcitabine Efficacy in Pancreatic Cancer: HuR Up-regulates the Expression of the Gemcitabine Metabolizing Enzyme Deoxycytidine Kinase
Christina L. Costantino et al.
CANCER RESEARCH (2009)
Nuclear functions of heterogeneous nuclear ribonucleoproteins A/B
Yaowu He et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2009)
Essential role of the RNA-binding protein HuR in progenitor cell survival in mice
Mallika Ghosh et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Upregulation of Hypoxia-inducible Factor-1α mRNA and its Clinical Significance in Non-small Cell Lung Cancer
Tomofumi Yohena et al.
JOURNAL OF THORACIC ONCOLOGY (2009)
The RNA-Binding Protein Elavl1/HuR Is Essential for Placental Branching Morphogenesis and Embryonic Development
Vicky Katsanou et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
The Expression of RNA-Binding Protein HuR in Non-Small Cell Lung Cancer Correlates with Vascular Endothelial Growth Factor-C Expression and Lymph Node Metastasis
Jun Wang et al.
ONCOLOGY (2009)
Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR
Anke Doller et al.
CELLULAR SIGNALLING (2008)
BARRIERS TO SUCCESSFUL DELIVERY OF SHORT INTERFERING RNA AFTER SYSTEMIC ADMINISTRATION
Paul J. White
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2008)
Nuclear HuR accumulation through phosphorylation by Cdk1
Hyeon Ho Kim et al.
GENES & DEVELOPMENT (2008)
Posttranslational modification of the AU-Rich element binding protein HuR by protein kinase C delta elicits angiotensin II-induced stabilization and nuclear export of clooxygenase 2 mRNA
Anke Doller et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
miR-519 reduces cell proliferation by lowering RNA-binding protein HuR levels
Kotb Abdelmohsen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The β-catenin/TCF4 pathway modifies alternative splicing through modulation of SRp20 expression
Vania Goncalves et al.
RNA (2008)
Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR
Nicole-Claudia Meisner et al.
NATURE CHEMICAL BIOLOGY (2007)
RNA-binding proteins: modular design for efficient function
Bradley M. Lunde et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)
Protein kinase Cα-dependent phosphorylation of the mRNA-stabilizing factor HuR:: Implications for posttranscriptional regulation of cyclooxygenase-2
Anke Doller et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Posttranscriptional orchestration of an anti-apoptotic program by HuR
Kotb Abdelmohsen et al.
CELL CYCLE (2007)
Stabilization of Snail by HuR in the process of hydrogen peroxide induced cell migration
Rui Dong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
Kotb Abdelmohsen et al.
MOLECULAR CELL (2007)
Nanotechnological applications in medicine
Shelton D. Caruthers et al.
CURRENT OPINION IN BIOTECHNOLOGY (2007)
Angiogenesis in cancer
Naoyo Nishida et al.
VASCULAR HEALTH AND RISK MANAGEMENT (2006)
The DICE-binding activity of KH domain 3 of hnRNP K is affected by c-Src-mediated tyrosine phosphorylation
Ana C. Messias et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cells
Xun Guo et al.
CANCER RESEARCH (2006)
Abraxane®, a novel Cremophor®-free, albumin-bound particle form of paclitaxel for the treatment of advanced non-small-cell lung cancer
M. R. Green et al.
ANNALS OF ONCOLOGY (2006)
The Role of PTB in Insulin mRNA Stability Control
Rickard G. Fred et al.
CURRENT DIABETES REVIEWS (2006)
Alterations in the tissue inhibitor of metalloproteinase-3 (TIMP-3) are found frequently in human colorectal turnours displaying either microsatellite stability (MSS) or instability (MSI)
WM Brueckl et al.
CANCER LETTERS (2005)
Posttranscriptional suppression of interleukin-6 production by human cytomegalovirus
C Gealy et al.
JOURNAL OF VIROLOGY (2005)
Identification of a target RNA motif for RNA-binding protein HuR
IL de Silanes et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Mechanisms of gene silencing by double-stranded RNA
G Meister et al.
NATURE (2004)
ATP potentiates interleukin-1β-induced MMP-9 expression in mesangial cells via recruitment of the ELAV protein HuR
A Huwiler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Role of the RNA-binding protein HuR in colon carcinogenesis
IL de Silanes et al.
ONCOGENE (2003)
Stabilization of urokinase and urokinase receptor mRNAs by HuR is linked to its cytoplasmic accumulation induced by activated mitogen-activated protein kinase-activated protein kinase 2
H Tran et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Messenger-RNA-binding proteins and the messages they carry
G Dreyfuss et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
HuR and mRNA stability
CM Brennan et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2001)
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