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Rabies burden in Cote d'Ivoire

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ACTA TROPICA
卷 226, 期 -, 页码 -

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DOI: 10.1016/j.actatropica.2021.106249

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In Côte d'Ivoire, the underreporting of rabies cases and the financial burden of rabies are highlighted. A study analyzing bite records and household survey data estimated a significantly higher number of deaths and costs associated with rabies compared to official data.
Background: In Co circumflex accent te d'Ivoire, just as in the majority of developing countries, rabies cases are underestimated. The official data are based on passive surveillance studies which cannot provide true estimates. Therefore, the economic and health burden of rabies is underestimated.& nbsp;To be able to better estimate the true burden of rabies, this study looked at surveillance data of bite records and household survey.& nbsp;Methodology: The data was collected from a cross-sectional survey of 8004 households, of which 4002 were in the Department of Bouake acute accent and 4002 in the Department of San Pedro. Further data was collected from Human Rabies control centres and from the respective veterinary services. We estimate the burden of rabies through data from the bites surveillance records. Human deaths from rabies were estimated using a series of probability steps to determine the likelihood of clinical rabies in a person after being bitten by a suspected rabid dog. Monte Carlo simulations of a series of interconnected probabilities were used to estimate the rabies burden in the country.& nbsp;Results: The number of deaths from rabies was estimated at 637deaths per year [95% CI 442-849] and human mortality from rabies was estimated at 2.61 per 100 & PRIME;000 [95% CI 1.81-3.56], which represents 24-47 times more cases than the official data. Deaths due to rabies are responsible for 23,252 Disability Adjusted Life Years (DALY) lost each year [95% CI 16,122-30,969]. The estimated annual cost of rabies is 40.15 million USD [95% CI 27.8-53.4]. Overall, 99% of the cost was due to premature deaths. The cost of post-exposure prophylaxis was estimated at 1.6 million USD and represented 1% of the overall cost of rabies.& nbsp;Conclusion: This study highlights the underreporting of rabies cases by the official health information system in Co circumflex accent te d'Ivoire and the annual financial losses related to rabies are equivalent to the estimated cost of the elimination of rabies by 2030. Thus, investing in the fight against in Co circumflex accent te d'Ivoire will be cost effective.

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