期刊
ACTA RADIOLOGICA
卷 64, 期 1, 页码 20-31出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/02841851211065925
关键词
Abdomen; gastrointestinal; magnetic resonance imaging; endoscopy; radiation therapy; oncology; rectum; primary neoplasms
The combined use of MRI and endoscopy tends to improve the diagnostic performance for assessing complete tumor response after neoadjuvant chemoradiotherapy in rectal cancer. However, there is considerable heterogeneity between studies.
Background The diagnostic performance of magnetic resonance imaging (MRI) modalities and/or endoscopy for assessing complete response in rectal cancer after neoadjuvant chemoradiotherapy (nCRT) is unclear. Purpose To summarize existing evidence on the diagnostic performance of diffusion-weighted MRI, perfusion-weighted MRI, T2-weighted MR tumor regression grade, and/or endoscopy for assessing complete tumor response after nCRT. Material and Methods MEDLINE and Embase databases were searched. The PRISMA guidelines were followed. Sensitivity, specificity, negative predictive, and positive predictive values were retrieved from included studies. Results In total, 81 studies were eligible for inclusion. Evidence suggests that combined use of MRI and endoscopy tends to improve the diagnostic performance compared to single imaging modality. The positive predictive value of a complete response varies substantially between studies. There is considerable heterogeneity between studies. Conclusion Combined re-staging tends to improve diagnostic performance compared to single imaging modality, but the vast majority of studies fail to offer true clinical value due to the study heterogeneity.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据