4.8 Article

Multifunctional Size-Expandable Nanomedicines Enhance Tumor Accumulation and Penetration for Synergistic Chemo-Photothermal Therapy

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Chemistry, Multidisciplinary

Tumor Acidity and Near-Infrared Light Responsive Dual Drug Delivery Polydopamine-Based Nanoparticles for Chemo-Photothermal Therapy

Rangrang Fan et al.

Summary: The development of folic acid functionalized polydopamine nanoparticles for dual delivery of doxorubicin and epigallocatechin-3-gallate has shown promising results in enhancing cellular uptake and anti-tumor efficacy with the assistance of near-infrared light. In vivo studies demonstrate improved drug accumulation, penetration, and retention in tumors, leading to significant suppression of tumor growth and improved survival rates in breast cancer-bearing mice. These nanoparticles have the potential to serve as an effective nanoscale vector for enhanced cancer therapy.

ADVANCED FUNCTIONAL MATERIALS (2021)

Review Chemistry, Multidisciplinary

Shape Transformable Strategies for Drug Delivery

Wenfeng Jia et al.

Summary: Nanoparticle shape significantly influences drug delivery efficacy, with transformable shapes achieved through internal or external stimuli enhancing delivery efficiency in time and space. This promising prospect may lead to improved cancer treatment in the future.

ADVANCED FUNCTIONAL MATERIALS (2021)

Article Engineering, Biomedical

Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy

Nasha Qiu et al.

Summary: CEL not only induces strong immunogenic cell death (ICD), but also downregulates the expression of PD-L1 in tumor cells. This allows CEL to activate dendritic cells (DCs) and T-cells simultaneously, while interrupting the PD-1/PD-L1 signaling pathway between T-cells and tumor cells. This approach shows promise as a more cost-effective immunotherapy strategy against melanoma compared to traditional immune checkpoint inhibitors.

BIOMATERIALS (2021)

Review Chemistry, Multidisciplinary

Gain an advantage from both sides: Smart size-shrinkable drug delivery nanosystems for high accumulation and deep penetration

Shuang Bai et al.

Summary: The first generation of nanomedicine shows superior performance compared to traditional anticancer therapeutics in clinical treatment of cancer, but poor tumor penetration has been a major obstacle. Recently, smart size shrinkable drug delivery nanosystems have effectively improved this situation by maintaining a relatively large size in circulation system and turning into smaller particles at the tumor site to enhance tumor penetration.

NANO TODAY (2021)

Review Pharmacology & Pharmacy

Hyperthermia and smart drug delivery systems for solid tumor therapy

A. L. B. Seynhaeve et al.

ADVANCED DRUG DELIVERY REVIEWS (2020)

Article Multidisciplinary Sciences

Escherichia coli adhesion portion FimH functions as an adjuvant for cancer immunotherapy

Wei Zhang et al.

NATURE COMMUNICATIONS (2020)

Article Nanoscience & Nanotechnology

Small Morph Nanoparticles for Deep Tumor Penetration via Caveolae-Mediated Transcytosis

Zipeng Zhang et al.

ACS APPLIED MATERIALS & INTERFACES (2020)

Article Chemistry, Multidisciplinary

Stimuli-responsive nano-assemblies for remotely controlled drug delivery

Fangyuan Li et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Review Oncology

Clinical development and potential of photothermal and photodynamic therapies for cancer

Xingshu Li et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2020)

Article Nanoscience & Nanotechnology

Intelligent Size-Changeable Nanoparticles for Enhanced Tumor Accumulation and Deep Penetration

Wenqi Yu et al.

ACS APPLIED BIO MATERIALS (2020)

Review Chemistry, Multidisciplinary

Size-Transformable Nanostructures: From Design to Biomedical Applications

Xiaodong Zhang et al.

ADVANCED MATERIALS (2020)

Review Immunology

Enhancing cancer immunotherapy with nanomedicine

Darrell J. Irvine et al.

NATURE REVIEWS IMMUNOLOGY (2020)

Review Oncology

PI3K/Akt/mTOR inhibitors in cancer: At the bench and bedside

Ali S. Alzahrani

SEMINARS IN CANCER BIOLOGY (2019)

Article Chemistry, Physical

Development and characterization of dual sensitive poly(N,N-diethyl acrylamide) grafted alginate microparticles

Nuran Isiklan et al.

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS (2019)

Article Chemistry, Multidisciplinary

Dandelion-Like Tailorable Nanoparticles for Tumor Microenvironment Modulation

Qin Guo et al.

ADVANCED SCIENCE (2019)

Article Chemistry, Multidisciplinary

Enhanced Antitumor Efficacy by a Cascade of Reactive Oxygen Species Generation and Drug Release

Sheng Wang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Chemistry, Multidisciplinary

Photothermal Therapy Generates a Thermal Window of Immunogenic Cell Death in Neuroblastoma

Elizabeth E. Sweeney et al.

Review Medicine, Research & Experimental

Stimuli-Responsive Nanomedicines for Overcoming Cancer Multidrug Resistance

Lei Zhou et al.

THERANOSTICS (2018)

Review Cell Biology

The HSP90 chaperone machinery

Florian H. Schopf et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Review Chemistry, Multidisciplinary

Design and Functionalization of the NIR-Responsive Photothermal Semiconductor Nanomaterials for Cancer Theranostics

Xiaojuan Huang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2017)

Review Pharmacology & Pharmacy

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Tarun Ojha et al.

ADVANCED DRUG DELIVERY REVIEWS (2017)

Article Chemistry, Multidisciplinary

Facile Generation of Tumor-pH-Labile Linkage-Bridged Block Copolymers for Chemotherapeutic Delivery

Chun-Yang Sun et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)

Article Materials Science, Biomaterials

Stimuli-responsive polymers for anti-cancer drug delivery

Weiren Cheng et al.

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2014)

Review Immunology

Immunogenic Cell Death in Cancer Therapy

Guido Kroemer et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

Review Chemistry, Multidisciplinary

Cellular Uptake, Intracellular Trafficking, and Cytotoxicity of Nanomaterials

Feng Zhao et al.

Article Nanoscience & Nanotechnology

Effect of Surface Charge on the Cellular Uptake and Cytotoxicity of Fluorescent Labeled Cellulose Nanocrystals

Khaled A. Mahmoud et al.

ACS APPLIED MATERIALS & INTERFACES (2010)

Review Polymer Science

Stimuli-reponsive polymers and their bioconjugates

ES Gil et al.

PROGRESS IN POLYMER SCIENCE (2004)

Article Multidisciplinary Sciences

Nanoshell-mediated near-infrared thermal therapy of tumors under magnetic resonance guidance

LR Hirsch et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)