相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Comprehensive analysis of chemokine-induced cAMP-inhibitory responses using a real-time luminescent biosensor
Virginia Felouzis et al.
CELLULAR SIGNALLING (2016)
Leucine-rich repeat kinase 2 positively regulates inflammation and down-regulates NF-κB p50 signaling in cultured microglia cells
Isabella Russo et al.
JOURNAL OF NEUROINFLAMMATION (2015)
Toll-Like Receptors Promote Mitochondrial Translocation of Nuclear Transcription Factor Nuclear Factor of Activated T-Cells in Prolonged Microglial Activation
Bo Ma et al.
JOURNAL OF NEUROSCIENCE (2015)
LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase
Insup Choi et al.
NATURE COMMUNICATIONS (2015)
Ribosomal Protein s15 Phosphorylation Mediates LRRK2 Neurodegeneration in Parkinson's Disease
Ian Martin et al.
CELL (2014)
Leucine-rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER-Golgi export
Hyun Jin Cho et al.
EMBO JOURNAL (2014)
LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity
Loukia Parisiadou et al.
NATURE NEUROSCIENCE (2014)
Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats
Joao P. L. Daher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Roles of the Drosophila LRRK2 homolog in Rab7-dependent lysosomal positioning
Mark W. Dodson et al.
HUMAN MOLECULAR GENETICS (2012)
The Soluble Isoform of CX3CL1 Is Necessary for Neuroprotection in a Mouse Model of Parkinson's Disease
Josh M. Morganti et al.
JOURNAL OF NEUROSCIENCE (2012)
LRRK2 Inhibition Attenuates Microglial Inflammatory Responses
Mark S. Moehle et al.
JOURNAL OF NEUROSCIENCE (2012)
Syk Regulates Multiple Signaling Pathways Leading to CX3CL1 Chemotaxis in Macrophages
Haein Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
CX3CL1 reduces neurotoxicity and microglial activation in a rat model of Parkinson's disease
Mibel M. Pabon et al.
JOURNAL OF NEUROINFLAMMATION (2011)
A QUICK Screen for Lrrk2 Interaction Partners - Leucine-rich Repeat Kinase 2 is Involved in Actin Cytoskeleton Dynamics
Andrea Meixner et al.
MOLECULAR & CELLULAR PROTEOMICS (2011)
The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease
Zhihua Liu et al.
NATURE IMMUNOLOGY (2011)
Regulation of LRRK2 Expression Points to a Functional Role in Human Monocyte Maturation
Jonathan Thevenet et al.
PLOS ONE (2011)
Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
Stephan Gehrke et al.
NATURE (2010)
The myeloid cells of the central nervous system parenchyma
Richard M. Ransohoff et al.
NATURE (2010)
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
Martin Fuhrmann et al.
NATURE NEUROSCIENCE (2010)
Regulation of Tau Pathology by the Microglial Fractalkine Receptor
Kiran Bhaskar et al.
NEURON (2010)
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
Javier Alegre-Abarrategui et al.
HUMAN MOLECULAR GENETICS (2009)
NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease
Nicholas H. Varvel et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
Phosphorylation of Ezrin/Radixin/Moesin Proteins by LRRK2 Promotes the Rearrangement of Actin Cytoskeleton in Neuronal Morphogenesis
Loukia Parisiadou et al.
JOURNAL OF NEUROSCIENCE (2009)
Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
Xian Lin et al.
NEURON (2009)
Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila
Yuzuru Imai et al.
EMBO JOURNAL (2008)
LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity
Mahaboobi Jaleel et al.
BIOCHEMICAL JOURNAL (2007)
Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking
Chen Lai et al.
JOURNAL OF NEUROSCIENCE (2006)
Control of microglial neurotoxicity by the fractalkine receptor
Astrid E. Cardona et al.
NATURE NEUROSCIENCE (2006)
Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (fractalkine)
JC Gevrey et al.
JOURNAL OF IMMUNOLOGY (2005)
Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress
HB Cai et al.
JOURNAL OF NEUROSCIENCE (2005)
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
A Nimmerjahn et al.
SCIENCE (2005)
Interleukin (IL)-15 and IL-2 reciprocally regulate expression of the chemokine receptor CX3CR1 through selective NFAT1- and NFAT2-dependent mechanisms
J Barlic et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, during acute and chronic inflammation in the rodent CNS
PM Hughes et al.
GLIA (2002)
Analysis of fractalkine receptor CX3CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
S Jung et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)