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Expression of distinct classes of titin isoforms in striated and smooth muscles by alternative splicing, and their conserved interaction with filamins
Siegfried Labeit et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
FHL2/SLIM3 decreases cardiomyocyte survival by inhibitory interaction with sphingosine kinase-1
Jianxin Sun et al.
CIRCULATION RESEARCH (2006)
Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo
Christian C. Witt et al.
EMBO JOURNAL (2006)
Pharmacological- and gene therapy-based inhibition of protein kinase Cα/β enhances cardiac contractility and attenuates heart failure
Michael Hambleton et al.
CIRCULATION (2006)
Protein kinase-A phosphorylates titin in human heart muscle and reduces myofibrillar passive tension
Martina Krueger et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2006)
Four and a half LIM protein 1 binds myosin-binding protein C and regulates myosin filament formation and sarcomere assembly
MJ McGrath et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
BioGRID: a general repository for interaction datasets
Chris Stark et al.
NUCLEIC ACIDS RESEARCH (2006)
Dimerization of the cardiac ankyrin protein CARP: Implications for MARP titin-based signaling
Stephanie H. Witt et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2005)
Functional analysis of titin/connectin N2-B mutations found in cardiomyopathy
Yuji Matsumoto et al.
JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2005)
Calpain 1-titin interactions concentrate calpain 1 in the Z-band edges and in the N2-line region within the skeletal myofibril
F Raynaud et al.
FEBS JOURNAL (2005)
Phosphorylation of titin modulates passive stiffness of cardiac muscle in a titin isoform-dependent manner
N Fukuda et al.
JOURNAL OF GENERAL PHYSIOLOGY (2005)
Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart
CA Opitz et al.
CIRCULATION RESEARCH (2004)
Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium
S Lahmers et al.
CIRCULATION RESEARCH (2004)
PKC-α regulates cardiac contractility and propensity toward heart failure
JC Braz et al.
NATURE MEDICINE (2004)
Association of the chaperone αB-crystallin with titin in heart muscle
B Bullard et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Induction and myofibrillar targeting of CARP, and suppression of the Nkx2.5 pathway in the MDM mouse with impaired titin-based signaling
CC Wittt et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
The SRF target gene Fhl2 antagonizes RhoA/MAL-dependent activation of SRF
U Philippar et al.
MOLECULAR CELL (2004)
The LIM-only proteins FHL2 and FHL3 interact with α- and β-subunits of the muscle α7β1 integrin receptor
T Samson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and β-catenin
C Labalette et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Differential actin binding along the PEVK domain of skeletal muscle titin
A Nagy et al.
JOURNAL OF CELL SCIENCE (2004)
The LIM domain: From the cytoskeleton to the nucleus
JL Kadrmas et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
The Ankrd2 protein, a link between the sarcomere and the nucleus in skeletal muscle
S Kojic et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Common genomic response in different mouse models of β-adrenergic-induced cardiomyopathy
V Gaussin et al.
CIRCULATION (2003)
The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules
MK Miller et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
FHL3 is an actin-binding protein that regulates α-actinin-mediated actin bundling -: FHL3 localizes to actin stress fibers and enhances cell spreading and stress fiber disassembly
ID Coghill et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Skeletal muscle LIM protein 1 regulates integrinmediated myoblast adhesion, spreading, and migration
PA Robinson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
Identification of the LIM protein FHL2 as a coactivator of β-catenin
Y Wei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals
K Ikeda et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2
S Lange et al.
JOURNAL OF CELL SCIENCE (2002)
Reverse engineering of the giant muscle protein titin
HB Li et al.
NATURE (2002)
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis
PD Gottlieb et al.
NATURE GENETICS (2002)
Titin mutations as the molecular basis for dilated cardiomyopathy
M Itoh-Satoh et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)
Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin
XL Xu et al.
NATURE GENETICS (2002)
The muscular dystrophy with myositis (mdm) mouse mutation disrupts a skeletal muscle-specific domain of titin
SM Garvey et al.
GENOMICS (2002)
Different molecular mechanics displayed by titin's constitutively and differentially expressed tandem Ig segments
K Watanabe et al.
JOURNAL OF STRUCTURAL BIOLOGY (2002)
PEVK domain of titin: An entropic spring with actin-binding properties
WA Linke et al.
JOURNAL OF STRUCTURAL BIOLOGY (2002)
The complete gene sequence of titin, expression of an unusual ≈700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system
ML Bang et al.
CIRCULATION RESEARCH (2001)
Interaction between PEVK-titin and actin filaments - Origin of a viscous force component in cardiac myofibrils
M Kulke et al.
CIRCULATION RESEARCH (2001)
Structural and functional studies of titin's fn3 modules reveal conserved surface patterns and binding to myosin S1 - A possible role in the frank-starling mechanism of the heart
C Muhle-Goll et al.
JOURNAL OF MOLECULAR BIOLOGY (2001)
Titin-actin interaction in mouse myocardium:: Passive tension modulation and its regulation by calcium/S100A1
R Yamasaki et al.
BIOPHYSICAL JOURNAL (2001)
Myopalladin, a novel 145-kilodalton sarcomeric protein with multiple roles in Z-disc and I-band protein assemblies
ML Bang et al.
JOURNAL OF CELL BIOLOGY (2001)
Modular motif, structural folds and affinity profiles of the PEVK segment of human fetal skeletal muscle titin
G Gutierrez-Cruz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A family of LIM-only transcriptional coactivators: Tissue-specific expression and selective activation of CREB and CREM
GM Fimia et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
DRAL is a p53-responsive gene whose four and a half LIM domain protein product induces apoptosis
FA Scholl et al.
JOURNAL OF CELL BIOLOGY (2000)
FHL2 (SLIM3) is not essential for cardiac development and function
PH Chu et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
FHL2, a novel tissue-specific coactivator of the androgen receptor
JM Müller et al.
EMBO JOURNAL (2000)
The function of alpha-crystallin in vision
J Horwitz
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2000)
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