Simulation of Inferior Rectus Muscle Behavior in Patients with Hypertrophic Thyroid Eye Disease Using Computational Biomechanics

In this study, a technique for the computational simulation of hypertrophy of the inferior rectus muscle, which is one of the main causes of proptosis in patients with thyroid eye disease, was proposed, and the locations with the estimated maximum stress from the computational simulation results were examined and compared with the clinical and surgical locations. A series of simulations of hypertrophy of the inferior rectus muscle was performed using single and combined loads. The behavior of the inferior rectus muscle, the eye rotation, and proptosis according to the loading condition were examined, and optimal loading conditions have been suggested for the simulation of hypertrophy of the inferior rectus muscle. In addition, the supplementary data to be considered during the selection of the surgical location and range have been provided.

Automated summary

This study proposed a computational simulation technique for the hypertrophy of the inferior rectus muscle, examined the behavior of the muscle and eye movement under different loading conditions, and suggested optimal loading conditions for simulation. Supplementary data for the selection of surgical location and range were also provided.