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Comparative immunogenicity of mRNA and inactivated vaccines against COVID-19

LANCET MICROBE (2021)

Correlates of Vaccine-Induced Protection against SARS-CoV-2

Till Koch et al.

Summary: The article discusses the challenges and developments brought by the COVID-19 pandemic, emphasizing the importance of vaccines in combating the outbreak. It mentions the progress and challenges of various vaccine candidates. The article also delves into vaccine-induced immune responses and immunological markers linked to protection, exploring possible methods for evaluating vaccines in the future.

VACCINES (2021)

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Article Biochemistry & Molecular Biology

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

David S. Khoury et al.

Summary: The level of neutralizing antibodies is closely related to immune protection against COVID-19, playing a crucial role in protecting against detected infection and severe infection. Studies have shown that neutralizing titers will decline over time after vaccination, leading to decreased protection against SARS-CoV-2 infection.

NATURE MEDICINE (2021)

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Article Immunology

Evidence for antibody as a protective correlate for COVID-19 vaccines

Kristen A. Earle et al.

Summary: The study found a strong correlation between antibody titers and efficacy when assessing different COVID-19 vaccines, supporting the use of post-immunization antibody titers as the basis for establishing a correlate of protection for COVID-19 vaccines.

VACCINE (2021)

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Article Microbiology

Evaluation of a SARS-CoV-2 Surrogate Virus Neutralization Test for Detection of Antibody in Human, Canine, Cat, and Hamster Sera

Ranawaka A. P. M. Perera et al.

Summary: The surrogate virus neutralization test (sVNT) showed high sensitivity and specificity compared to the plaque reduction neutralization test (PRNT90) in human, canine, cat, and hamster sera. There was no cross-reactivity to other coronaviruses in both SARS-CoV-2 sVNT and PRNT90, except for cross-reactivity to SARS-CoV-1 in sVNT.

JOURNAL OF CLINICAL MICROBIOLOGY (2021)

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Article Infectious Diseases

Serological assays for severe acute respiratory syndrome coronavirus 2 (BARS-CoV-2), March 2020

Ranawaka A. P. M. Perera et al.

EUROSURVEILLANCE (2020)

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Comparative immunogenicity of mRNA and inactivated vaccines against COVID-19

相关参考文献

Correlates of Vaccine-Induced Protection against SARS-CoV-2

Neutralizing antibody levels are highly predictive of immune protection from symptomatic SARS-CoV-2 infection

Evidence for antibody as a protective correlate for COVID-19 vaccines

Evaluation of a SARS-CoV-2 Surrogate Virus Neutralization Test for Detection of Antibody in Human, Canine, Cat, and Hamster Sera

Serological assays for severe acute respiratory syndrome coronavirus 2 (BARS-CoV-2), March 2020

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