期刊
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
卷 38, 期 -, 页码 E2122-E2126出版社
WILEY-BLACKWELL
DOI: 10.1002/hed.24397
关键词
carbon ion radiotherapy; radiotherapy; adenoid cystic carcinoma; tongue base; head and neck cancer
资金
- Research Project with Heavy Ions at the National Institute of Radiological Sciences (NIRS)-Heavy Ion Medical Accelerator in Chiba (HIMAC)
- Grants-in-Aid for Scientific Research [26860970] Funding Source: KAKEN
Background. Most cases of adenoid cystic carcinoma (ACC) of the tongue base are radioresistant, and are diagnosed in the advanced stage. Therefore, we evaluated the safety and efficacy of carbon ion radiotherapy (C-ion RT) for locally advanced ACC of the tongue base. Methods. Eighteen patients with ACC of the tongue base were treated with C-ion RT between May 2002 and April 2014. Seventeen patients had T4a disease and 1 patient had T2 disease before C-ion RT. Results. The median follow-up period was 57 months (range, 10-132 months). The 5-year local control rate was 92%. The 5-year overall survival (OS) and disease-free survival (DFS) rates were 72% and 44%, respectively. Regarding late reactions, 2 patients developed grade 3 mandible osteoradionecrosis, and 1 had grade 3 hemorrhage of the tongue base. Conclusion. C-ion RT was effective with acceptable toxicities for locally advanced ACC of the tongue base. (C) 2016 Wiley Periodicals, Inc.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据