Post COVID-19 Syndrome (Long COVID) and Diabetes: Challenges in Diagnosis and Management

Background and Aims: Post Covid-19 syndrome (PCS) is a major cause of morbidity. In this article we intend to review the association and consequences of PCS and diabetes. Methods: We reviewed all studies on Long Covid, Post COVID-19 Syndrome and diabetes in PubMed and Google Scholar. Results: The symptoms of PCS can be due to organ dysfunction, effects of hospitalisation and drugs, or unrelated to these. Type 2 diabetes mellitus has a bidirectional relationship with COVID-19. Presence of diabetes also influences PCS via various pathophysiological mechanisms. COVID-19 can add to or exacerbate tachycardia, sarcopenia (and muscle fatigue), and microvascular dysfunction (and organ damage) in patients with diabetes. Conclusion: PCS in patients with diabetes could be detrimental in multiple ways. Strict control of diabetes and other comorbidities, supervised rehabilitation and physical exercise, and optimal nutrition could help in reducing and managing PCS. (C) 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Automated summary

This study reviewed the association and consequences of Post Covid-19 syndrome (PCS) and diabetes, finding that PCS symptoms can be caused by various factors including organ dysfunction, effects of hospitalization and drugs, and diabetes also influences PCS through multiple pathophysiological mechanisms.