期刊
JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY
卷 89, 期 6, 页码 537-550出版社
AMER PSYCHOLOGICAL ASSOC
DOI: 10.1037/ccp0000650
关键词
transdiagnostic; sleep; circadian; serious mental illness; dissemination
资金
- National Institute of Mental Health [MH105513]
The study showed that TranS-C intervention significantly improved patients' functional impairment, psychiatric symptoms, and sleep and circadian functioning, with effects maintained in the long-term follow-up. This treatment also had positive effects on improving sleep efficiency, reducing wake time, and enhancing sleep health composite score.
Objective: To determine if the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves functional impairment, psychiatric symptoms, and sleep and circadian functioning. Method: Adults diagnosed with serious mental illness (SMI) and sleep and circadian dysfunction (N = 121) were randomly allocated to TranS-C plus usual care (TranS-C + UC; n = 61; 8 individual weekly sessions) or 6 months of Usual Care followed by Delayed Treatment with TranS-C (UC-DT; n = 60). Schizophrenia (45%) and anxiety disorders (47%) were common. Blind assessments were conducted pre-treatment, post-treatment, and 6 months later (6FU). The latter two were the post-randomization points of interest. The location was Alameda County Behavioral Health Care Services (ACBHCS), a Community Mental Health Center (CMHC) in California. Results: For the primary outcomes, relative to UC-DT, TranS-C + UC was associated with reduction in functional impairment (b = -3.18, p = 0.025, d = -0.58), general psychiatric symptoms (b = -5.88, p = 0.001, d = -0.64), sleep disturbance (b = -5.55, p <.0001, d = -0.96), and sleep-related impairment (b = -9.14, p <.0001, d = -0.81) from pre-treatment to post-treatment. These effects were maintained to 6month follow-up (6FU; d = -0.42 to -0.82), except functional impairment (d = -0.37). For the secondary outcomes, relative to UC-DT, TranS-C + UC was associated with improvement in sleep efficiency and on the SleepHealth Composite score frompre-treatment to 6FU. TranS-C + UC was also associatedwith reduced total wake time and wake time variability from pre-treatment to post-treatment, as well as reduced hallucinations and delusions, bedtime variability, and actigraphy measured waking activity count variability from pre-treatment to 6FU. Conclusions: A novel transdiagnostic treatment, delivered within a CMHC setting, improves selected measures of functioning, symptoms of comorbid disorders, and sleep and circadian outcomes.
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