相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A summary of the current drug interaction guidance from the European Medicines Agency and considerations of future updates
Susan Cole et al.
DRUG METABOLISM AND PHARMACOKINETICS (2020)
A Comprehensive Whole-Body Physiologically Based Pharmacokinetic Drug-Drug-Gene Interaction Model of Metformin and Cimetidine in Healthy Adults and Renally Impaired Individuals
Nina Hanke et al.
CLINICAL PHARMACOKINETICS (2020)
A Physiologically-Based Pharmacokinetic (PBPK) Model Network for the Prediction of CYP1A2 and CYP2C19 Drug-Drug-Gene Interactions with Fluvoxamine, Omeprazole, S-mephenytoin, Moclobemide, Tizanidine, Mexiletine, Ethinylestradiol, and Caffeine
Tobias Kanacher et al.
PHARMACEUTICS (2020)
Consideration of a Credibility Assessment Framework in Model-Informed Drug Development: Potential Application to Physiologically-Based Pharmacokinetic Modeling and Simulation
Colleen Kuemmel et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2020)
Physiologically Based Pharmacokinetic Models for Prediction of Complex CYP2C8 and OATP1B1 (SLCO1B1) Drug-Drug-Gene Interactions: A Modeling Network of Gemfibrozil, Repaglinide, Pioglitazone, Rifampicin, Clarithromycin and Itraconazole
Denise Tuerk et al.
CLINICAL PHARMACOKINETICS (2019)
Physiologically Based Pharmacokinetic Modeling in Regulatory Science: An Update From the US Food and Drug Administration's Office of Clinical Pharmacology
Manuela Grimstein et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Recommendations for the Design of Clinical Drug-Drug Interaction Studies With Itraconazole Using a Mechanistic Physiologically-Based Pharmacokinetic Model
Yuan Chen et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2019)
Physiologically-Based Pharmacokinetic Models for CYP1A2 Drug-Drug Interaction Prediction: A Modeling Network of Fluvoxamine, Theophylline, Caffeine, Rifampicin, and Midazolam
Hannah Britz et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2019)
Physiologically Based Pharmacokinetic Model of Itraconazole and Two of Its Metabolites to Improve the Predictions and the Mechanistic Understanding of CYP3A4 Drug-Drug Interactions
Luna Prieto Garcia et al.
DRUG METABOLISM AND DISPOSITION (2018)
Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children
Wangda Zhou et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2018)
PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin
Nina Hanke et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2018)
Prediction of drug-drug interactions using physiologically-based pharmacokinetic models of CYP450 modulators included in Simcyp software
Niloufar Marsousi et al.
BIOPHARMACEUTICS & DRUG DISPOSITION (2018)
Physiologically Based Pharmacokinetic Modeling in Regulatory Decision-Making at the European Medicines Agency
E. Luzon et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2017)
Validation of a Microdose Probe Drug Cocktail for Clinical Drug Interaction Assessments for Drug Transporters and CYP3A
T. Prueksaritanont et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2017)
Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation
S. F. Marshall et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2016)
Predictive Performance of Physiologically Based Pharmacokinetic and Population Pharmacokinetic Modeling of Renally Cleared Drugs in Children
W. Zhou et al.
CPT-PHARMACOMETRICS & SYSTEMS PHARMACOLOGY (2016)
Mechanism of Efavirenz Influence on Methadone Pharmacokinetics and Pharmacodynamics
E. D. Kharasch et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2012)
Sensitivity of Intravenous and Oral Alfentanil and Pupillary Miosis as Minimal and Noninvasive Probes for Hepatic and First-Pass CYP3A Induction
E. D. Kharasch et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2011)
Critique of the Two-Fold Measure of Prediction Success for Ratios: Application for the Assessment of Drug-Drug Interactions
Eleanor J. Guest et al.
DRUG METABOLISM AND DISPOSITION (2011)
Pharmacokinetics of intravenous and oral midazolam in plasma and saliva in humans:: usefulness of saliva as matrix for CYP3A phenotyping
Bettina Link et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2008)
Comparison of midazolam and simvastatin as cytochromc P450 3A probes
E Chung et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2006)
The effect of age, sex, and rifampin administration on intestinal and hepatic cytochrome P450 3A activity
JC Gorski et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2003)