CoS2/MoS2 Nanosheets with Enzymatic and Photocatalytic Properties for Bacterial Sterilization

Harvesting a remarkable antibacterial performance is a major point to choose enzymatic catalytic and photocatalytic coupling catalysts. Here, Co-Mo-S mixed metal sulfides (MMSs) were composed by tailoring the composition and energy of metal organic framework (MOF)-based precursors. When n(Co)/n(Mo) = 1:1, Co/Mo-MOF is in the lowest energy state and the vulcanized CoS2/MoS2 nanosheets (NSs) exhibit the best enzymatic property. With the inherent photocatalytic activity, CoS2/MoS2 NSs can degrade more than 90% of methylene blue, methyl orange, rhodamine B, and tetracycline hydrochloride within 1 h. Promoted by intrinsic photocatalytic properties, CoS2/MoS2 NSs exhibit outstanding mimic enzyme-mimicking abilities in a neutral medium, which solve the big problem that nanozymes can only work in acidic environments. Due to the collaboration of enzymatic and photocatalytic catalysis, center dot O-2(-) can be generated in a neutral, no H2O2, and dark system, which can effectively kill Escherichia coli and Staphylococcus aureus. In all, the design of MOFs with adjustable compositions, the breakthrough of enzymatic catalysis working in a neutral medium, and the innovation of sterilization independent of external conditions encourage the utilization in an open environment and the construction of multifunctional materials in biotechnology, biosensors, and biomedicine.

Automated summary

The use of enzymatic and photocatalytic coupling catalysts to achieve significant antibacterial performance has been achieved by tailoring the composition and energy levels of Co-Mo-S mixed metal sulfides derived from metal organic framework (MOF) precursors. The vulcanized CoS2/MoS2 nanosheets exhibit excellent enzymatic properties and can degrade various pollutants in a neutral environment. The collaboration of enzymatic and photocatalytic catalysis has led to the development of multifunctional materials with significant applications in biotechnology and biomedicine.