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Efficacy and Safety of Paromomycin for Visceral Leishmaniasis: A Systematic Review

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JOURNAL OF TROPICAL MEDICINE
卷 2021, 期 -, 页码 -

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HINDAWI LTD
DOI: 10.1155/2021/8629039

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Visceral leishmaniasis is a prevalent and commonly neglected tropical disease, with paromomycin being a frequently used drug in its treatment. However, there is a lack of comprehensive review on the action of paromomycin in the treatment of kala-azar.
Visceral leishmaniasis, also known as kala-azar is one of the most commonly neglected tropical diseases affecting a large number of rural and resource-limited people in South Asia, Africa, and South America. Paromomycin, an aminoglycoside drug, is frequently used for the treatment of visceral leishmaniasis. Despite limited therapies for visceral leishmaniasis and emerging drug resistance, a proper review on the action of paromomycin for kala-azar is lacking. This systematic review aims to look for the efficacy and safety aspects of paromomycin for the treatment of visceral leishmaniasis.

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