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Dried Blood Spot in Toxicology: Current Knowledge

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Article Medical Laboratory Technology

Evaluation of dried blood spots as alternative sampling material for serological detection of anti-SARS-CoV-2 antibodies using established ELISAs

Heike Weisser et al.

Summary: Findings from the study indicate that capillary blood samples obtained by finger prick (DBS) show high agreement and correlation with venous serum samples in detecting anti-SARS-CoV-2 antibodies using ELISA, suggesting the potential usability and robustness of DBS as sample material for antibody detection.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2021)

Article Toxicology

A comparison between two different dried blood substrates in determination of psychoactive substances in postmortem samples

Matteo Moretti et al.

Summary: The study analyzed various psychoactive substances in postmortem blood samples on different cards, showing generally good qualitative and quantitative correlation. It demonstrated that FTA cards are a good and hazard-free alternative for storing and analyzing psychoactive substances.

FORENSIC TOXICOLOGY (2021)

Article Biochemical Research Methods

Validation of dried blood spot sample modifications to two commercially available COVID-19 IgG antibody immunoassays

Theodore T. Zava et al.

Summary: The study validated the feasibility of using DBS samples for Coronavirus disease 2019 IgG antibody testing, showing comparable accuracy and reliability to serum samples with minimal kit modifications needed.

BIOANALYSIS (2021)

Article Medical Laboratory Technology

Analysis of SARS-CoV-2 antibodies from dried blood spot samples with the Roche Elecsys Immunochemistry method

Elizabeth Fontaine et al.

Summary: This study demonstrates the successful application of the Roche Elecsys anti-SARS-CoV-2 assay on capillary dried blood spot samples, showing high agreement with paired serum samples and good accuracy even after 9 days of collection. This indicates that dried blood spot samples are a reliable and convenient option for large-scale COVID-19 screening programs.

PRACTICAL LABORATORY MEDICINE (2021)

Article Medical Laboratory Technology

Evaluation of dried blood spots as alternative sampling material for serological detection of anti-SARS-CoV-2 antibodies using established ELISAs

Heike Weisser et al.

Summary: The study showed that DBS results had almost perfect agreement and high correlations with serum samples in both S1-based ELISA and NCP-based ELISA, indicating the potential for DBS to be used in large-scale epidemiological screening for antibodies against SARS-CoV-2.

CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2021)

Article Medical Laboratory Technology

Comparing Dried Blood Spots and Plasma Concentrations for Busulfan Therapeutic Drug Monitoring in Children

Ana Dilo et al.

THERAPEUTIC DRUG MONITORING (2020)

Review Medicine, General & Internal

Dried Blood Spot in Laboratory: Directions and Prospects

Kristina Malsagova et al.

DIAGNOSTICS (2020)

Editorial Material Biochemistry & Molecular Biology

Dried blood spots in therapeutic drug monitoring and toxicology

Sofie Velghe et al.

EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2018)

Review Public, Environmental & Occupational Health

Dried Blood Spots for Global Health Diagnostics and Surveillance: Opportunities and Challenges

Mark D. Lim

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Using dried blood spots to facilitate therapeutic drug monitoring of antiretroviral drugs in resource-poor regions

Urs Duthaler et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2018)

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Dried blood spots combined to an UPLC-MS/MS method for the simultaneous determination of drugs of abuse in forensic toxicology

Susana Sadler Simoes et al.

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2018)

Article Biochemical Research Methods

Determination of topiramate in dried blood spots using single-quadrupole gas chromatography-mass spectrometry after flash methylation with trimethylanilinium hydroxide

Roberta Zilles Hahn et al.

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES (2017)

Article Multidisciplinary Sciences

Dried Blood Spots - Preparing and Processing for Use in Immunoassays and in Molecular Techniques

Nico Gruener et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2015)

Review Pharmacology & Pharmacy

Therapeutic Drug Monitoring by Dried Blood Spot: Progress to Date and Future Directions

Abraham J. Wilhelm et al.

CLINICAL PHARMACOKINETICS (2014)

Review Biochemical Research Methods

Dried blood spots: Concepts, present status, and future perspectives in bioanalysis

Abhisheak Sharma et al.

DRUG TESTING AND ANALYSIS (2014)

Review Biochemical Research Methods

Spot them in the spot: analysis of abused substances using dried blood spots

Nele Sadones et al.

BIOANALYSIS (2014)

Review Toxicology

Dried blood spots in toxicology: from the cradle to the grave?

Christophe P. Stove et al.

CRITICAL REVIEWS IN TOXICOLOGY (2012)

Article Medicine, General & Internal

A new medical concept: The metallic profile

J. -P. Goulle et al.

REVUE DE MEDECINE INTERNE (2010)

Review Medical Laboratory Technology

Oral Fluid Testing for Drugs of Abuse

Wendy M. Bosker et al.

CLINICAL CHEMISTRY (2009)

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Determination of lead in blood by laser ablation ICP-TOF-MS analysis of blood spotted and dried on filter paper: a feasibility study

James V. Cizdziel

ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2007)