4.6 Article

A Microbial Monitoring System Demonstrated on the International Space Station Provides a Successful Platform for Detection of Targeted Microorganisms

期刊

LIFE-BASEL
卷 11, 期 6, 页码 -

出版社

MDPI
DOI: 10.3390/life11060492

关键词

microbial monitoring; qPCR; International Space Station (ISS); microbiome; Environmental Control and Life Support Systems (ECLSS); closed environment; microgravity

资金

  1. NASA ISS Office
  2. NASA AES Program
  3. NASA, KSC CIF Program

向作者/读者索取更多资源

The research explored the environmental monitoring systems and technologies needed in closed space environments, successfully testing an instrument for microbial monitoring. Tests conducted on the space station showed that this technology can effectively detect target microorganisms, enhancing crew safety.
Closed environments such as the International Space Station (ISS) and spacecraft for other planned interplanetary destinations require sustainable environmental control systems for manned spaceflight and habitation. These systems require monitoring for microbial contaminants and potential pathogens that could foul equipment or affect the health of the crew. Technological advances may help to facilitate this environmental monitoring, but many of the current advances do not function as expected in reduced gravity conditions. The microbial monitoring system (RAZOR(R) EX) is a compact, semi-quantitative rugged PCR instrument that was successfully tested on the ISS using station potable water. After a series of technical demonstrations between ISS and ground laboratories, it was determined that the instruments functioned comparably and provided a sample to answer flow in approximately 1 hour without enrichment or sample manipulation. Post-flight, additional advancements were accomplished at Kennedy Space Center, Merritt Island, FL, USA, to expand the instrument's detections of targeted microorganisms of concern such as water, food-borne, and surface microbes including Salmonella enterica serovar Typhimurium, Pseudomonas aeruginosa, Escherichia coli, and Aeromonas hydrophilia. Early detection of contaminants and bio-fouling microbes will increase crew safety and the ability to make appropriate operational decisions to minimize exposure to these contaminants.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据