相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Mechanism of substrate transport and inhibition of the human LAT1-4F2hc amino acid transporter
Renhong Yan et al.
CELL DISCOVERY (2021)
Cryo-EM structure of the human heteromeric amino acid transporter b0,+ AT-rBAT
Renhong Yan et al.
SCIENCE ADVANCES (2020)
Structural basis for amino acid exchange by a human heteromeric amino acid transporter
Di Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Consensus mutagenesis approach improves the thermal stability of system xc- transporter, xCT, and enables cryo-EM analyses
Kazumasa Oda et al.
PROTEIN SCIENCE (2020)
Structural insight into the substrate recognition and transport mechanism of the human LAT2-4F2hc complex
Renhong Yan et al.
CELL DISCOVERY (2020)
Functional characterization of the alanine-serine-cysteine exchanger of Carnobacterium sp AT7
Paola Bartoccioni et al.
JOURNAL OF GENERAL PHYSIOLOGY (2019)
Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex
Renhong Yan et al.
NATURE (2019)
Analysis of LPI-causing mutations on y+LAT1 function and localization
Bianca Maria Rotoli et al.
ORPHANET JOURNAL OF RARE DISEASES (2019)
Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc
Yongchan Lee et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
L amino acid transporter structure and molecular bases for the asymmetry of substrate interaction
Ekaitz Errasti-Murugarren et al.
NATURE COMMUNICATIONS (2019)
Dysfunctional LAT2 Amino Acid Transporter Is Associated With Cataract in Mouse and Humans
Emilia Boiadjieva Knopfel et al.
FRONTIERS IN PHYSIOLOGY (2019)
Discovery of Potent Inhibitors for the Large Neutral Amino Acid Transporter 1 (LAT1) by Structure-Based Methods
Natesh Singh et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Inhibition of the Alanine-Serine-Cysteine-1 Transporter by BMS-466442
Ivan R. Torrecillas et al.
ACS CHEMICAL NEUROSCIENCE (2019)
Insights into the Structure, Function, and Ligand Discovery of the Large Neutral Amino Acid Transporter 1, LAT1
Natesh Singh et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Structural basis for amino acid transport by the CAT family of SLC7 transporters
Katharina E. J. Jungnickel et al.
NATURE COMMUNICATIONS (2018)
Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss
Meritxell Espino Guarch et al.
ELIFE (2018)
Amino acid transporters revisited: New views in health and disease
Palanivel Kandasamy et al.
TRENDS IN BIOCHEMICAL SCIENCES (2018)
Asc-1 Transporter Regulation of Synaptic Activity via the Tonic Release of D-Serine in the Forebrain
Hagit Sason et al.
CEREBRAL CORTEX (2017)
The role of transmembrane segment 5 (TM5) in Na2 release and the conformational transition of neurotransmitter:sodium symporters toward the inward-open state
Sebastian Stolzenberg et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Amino acid homeostasis and signalling in mammalian cells and organisms
Stefan Broer et al.
BIOCHEMICAL JOURNAL (2017)
Two Na+ Sites Control Conformational Change in a Neurotransmitter Transporter Homolog
Sotiria Tavoulari et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Structure-activity relations of leucine derivatives reveal critical moieties for cellular uptake and activation of mTORC1-mediated signaling
Shushi Nagamori et al.
AMINO ACIDS (2016)
Shared Molecular Mechanisms of Membrane Transporters
David Drew et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 85 (2016)
Drugging Membrane Protein Interactions
Hang Yin et al.
ANNUAL REVIEW OF BIOMEDICAL ENGINEERING, VOL 18 (2016)
LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates
Arik A. Zur et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2016)
Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder
Dora C. Tarlungeanu et al.
CELL (2016)
Insights into the molecular basis for substrate binding and specificity of the wild-type L-arginine/agmatine antiporter AdiC
Huseyin Ilgu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Structural Insights Into Thyroid Hormone Transport Mechanisms of the L-Type Amino Acid Transporter 2
Katrin M. Hinz et al.
MOLECULAR ENDOCRINOLOGY (2015)
Tissue-based map of the human proteome
Mathias Uhlen et al.
SCIENCE (2015)
xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases
Lu Dai et al.
FRONTIERS IN MICROBIOLOGY (2015)
A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters
Lina Malinauskaite et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc
Albert Rosell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Conformational cycle and ion-coupling mechanism of the Na+/hydantoin transporter Mhp1
Kelli Kazmier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Expansion of the APC superfamily of secondary carriers
Ake Vastermark et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2014)
The SLC3 and SLC7 families of amino acid transporters
Dimitrios Fotiadis et al.
MOLECULAR ASPECTS OF MEDICINE (2013)
Structure-based ligand discovery for the Large-neutral Amino Acid Transporter 1, LAT-1
Ethan G. Geier et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Functional identification and characterization of sodium binding sites in Na symporters
Donald D. F. Loo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Sided Functions of an Arginine-Agmatine Antiporter Oriented in Liposomes
Ming-Feng Tsai et al.
BIOCHEMISTRY (2012)
Structure and mechanism of a glutamate-GABA antiporter
Dan Ma et al.
NATURE (2012)
Investigation of the sodium-binding sites in the sodium-coupled betaine transporter BetP
Kamil Khafizov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Substrate specificity and ion coupling in the Na+/betaine symporter BetP
Camilo Perez et al.
EMBO JOURNAL (2011)
Molecular basis of substrate-induced permeation by an amino acid antiporter
Lukasz Kowalczyk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: A possible target for combination therapy with anti-proliferative aminopeptidase inhibitors
Xuetao Fan et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Role of Transmembrane Domain 8 in Substrate Selectivity and Translocation of SteT, a Member of the L-Amino Acid Transporter (LAT) Family
Paola Bartoccioni et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mechanism of substrate recognition and transport by an amino acid antiporter
Xiang Gao et al.
NATURE (2010)
Mapping the human membrane proteome: a majority of the human membrane proteins can be classified according to function and evolutionary origin
Markus Sallman Almen et al.
BMC BIOLOGY (2009)
Structure of a prokaryotic virtual proton pump at 3.2 Å resolution
Yiling Fang et al.
NATURE (2009)
The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters
Lucy R. Forrest et al.
PHYSIOLOGY (2009)
Structure and Mechanism of an Amino Acid Antiporter
Xiang Gao et al.
SCIENCE (2009)
Structure and Mechanism of a Na+-Independent Amino Acid Transporter
Paul L. Shaffer et al.
SCIENCE (2009)
The xc- cystine/glutamate antiporter:: a mediator of pancreatic cancer growth with a role in drug resistance
M. Lo et al.
BRITISH JOURNAL OF CANCER (2008)
Lysinuric protein intolerance: Update and extended mutation analysis of the SLC7A7 gene
Maria Pia Sperandeo et al.
HUMAN MUTATION (2008)
Transport viewed as a catalytic process
Martin Klingenberg
BIOCHIMIE (2007)
Opinion - How many drug targets are there?
John P. Overington et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Structure and function of cationic amino acid transporters (CATs)
E. I. Closs et al.
JOURNAL OF MEMBRANE BIOLOGY (2006)
Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters
A Yamashita et al.
NATURE (2005)
New insights into cystinuria: 40 new mutations, genotype-phenotype correlation, and digenic inheritance causing partial phenotype
M Font-Llitjos et al.
JOURNAL OF MEDICAL GENETICS (2005)
Activation of system L heterodimeric amino acid exchangers by intracellular substrates
C Meier et al.
EMBO JOURNAL (2002)
Functional analysis of mutations in SLC7A9, and genotype-phenotype correlation in non-Type I cystinuria
M Font et al.
HUMAN MOLECULAR GENETICS (2001)