Development of an Electrochemical Immunosensor for Detection of Cardiac Troponin I at the Point-of-Care

Cardiac troponin I (cTnI) plays an important role in the assessment of various cardiac diseases. However, accurate detection of cTnI at the point-of-care (POC) remains unfeasible. In this study, we report the development of an electrochemical immunosensor designed for rapid and accurate cTnI detection in pre-hospital settings. Rapid cTnI analysis of whole blood samples was then performed. cTnI measurements were highly correlated with the results of the standard clinical laboratory method for cTnI detection. The results of this study suggest that the proposed POC immunosensor can deliver fast and accurate cTnI analysis in pre-hospital settings to achieve rapid diagnosis and guide patient management.

Automated summary

An electrochemical immunosensor was developed for rapid and accurate detection of cardiac troponin I in pre-hospital settings, showing highly correlated results with standard clinical laboratory methods. This suggests that the proposed point-of-care immunosensor can provide fast and accurate cTnI analysis for rapid diagnosis and patient management.