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INFLAMMATORY BOWEL DISEASES (2010)
Paneth's disease
Jan Wehkamp et al.
JOURNAL OF CROHNS & COLITIS (2010)
Evolving paradigms in the pathogenesis of IBD
Lloyd Mayer
JOURNAL OF GASTROENTEROLOGY (2010)
TOLL-LIKE RECEPTOR 2 AND MUC2 EXPRESSION ON HUMAN INTESTINAL EPITHELIAL CELLS BY GYMNOPHALLOIDES SEOI ADULT ANTIGEN
Ki-Deok Lee et al.
JOURNAL OF PARASITOLOGY (2010)
Multiple facets of intestinal permeability and epithelial handling of dietary antigens
S. Menard et al.
MUCOSAL IMMUNOLOGY (2010)
Enteric defensins are essential regulators of intestinal microbial ecology
Nita H. Salzman et al.
NATURE IMMUNOLOGY (2010)
Coexistence of passive and carrier-mediated processes in drug transport
Kiyohiko Sugano et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
The role of secretory antibodies in infection immunity
Richard A. Strugnell et al.
NATURE REVIEWS MICROBIOLOGY (2010)
OPINION Emerging role for the cytoskeleton as an organizer and regulator of translation
Seyun Kim et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
Session 9: Food ingredients, immunity and inflammation: animal and in vitro models New insights into the immunological effects of food bioactive peptides in animal models of intestinal inflammation
Fermin Sanchez de Medina et al.
PROCEEDINGS OF THE NUTRITION SOCIETY (2010)
Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease
Dorottya Nagy Szakal et al.
VIRCHOWS ARCHIV (2010)
Immune adaptations that maintain homeostasis with the intestinal microbiota
Lora V. Hooper et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function
Maria T. Abreu
NATURE REVIEWS IMMUNOLOGY (2010)
Barrier properties of mucus
Richard A. Cone
ADVANCED DRUG DELIVERY REVIEWS (2009)
Probiotic mixture VSL#3 protects the epithelial barrier by maintaining tight junction protein expression and preventing apoptosis in a murine model of colitis
Rudolf Mennigen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
The Tight Junction Protein Cingulin Regulates Gene Expression and RhoA Signaling
Sandra Citi et al.
MOLECULAR STRUCTURE AND FUNCTION OF THE TIGHT JUNCTION: FROM BASIC MECHANISMS TO CLINICAL MANIFESTATIONS (2009)
Mechanisms of Tight Junction Dysregulation in the SAMP1/YitFc Model of Crohn's Disease-like Ileitis
Brian K. Reuter et al.
MOLECULAR STRUCTURE AND FUNCTION OF THE TIGHT JUNCTION: FROM BASIC MECHANISMS TO CLINICAL MANIFESTATIONS (2009)
The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection
Nanda Burger-van Paassen et al.
BIOCHEMICAL JOURNAL (2009)
The Genetic Basis of Inflammatory Bowel Disease
Rachel Cooney et al.
DIGESTIVE DISEASES (2009)
Polymeric Binders Suppress Gliadin-Induced Toxicity in the Intestinal Epithelium
Maud Pinier et al.
GASTROENTEROLOGY (2009)
Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis
Liping Su et al.
GASTROENTEROLOGY (2009)
Celiac Disease: From Pathogenesis to Novel Therapies
Detlef Schuppan et al.
GASTROENTEROLOGY (2009)
Impaired intestinal barrier integrity in the colon of patients with irritable bowel syndrome: involvement of soluble mediators
T. Piche et al.
GUT (2009)
Inflammatory bowel disease: review from the aspect of genetics
Shunji Ishihara et al.
JOURNAL OF GASTROENTEROLOGY (2009)
Secretory IgA-Mediated Neutralization of Shigella flexneri Prevents Intestinal Tissue Destruction by Down-Regulating Inflammatory Circuits
Severine Boullier et al.
JOURNAL OF IMMUNOLOGY (2009)
Role of Intestinal Mucins in Innate Host Defense Mechanisms against Pathogens
Poonam Dharmani et al.
JOURNAL OF INNATE IMMUNITY (2009)
Junctional Adhesion Molecule A Interacts with Afadin and PDZ-GEF2 to Activate Rap1A, Regulate β1 Integrin Levels, and Enhance Cell Migration
Eric A. Severson et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
MECHANISMS OF DISEASE Inflammatory Bowel Disease
Clara Abraham et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2
Amit Tripathi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Structure and Biochemistry of Cadherins and Catenins
Lawrence Shapiro et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
Physiology and Function of the Tight Junction
James M. Anderson et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2009)
Intestinal mucosal barrier function in health and disease
Jerrold R. Turner
NATURE REVIEWS IMMUNOLOGY (2009)
Novel role of the vitamin D receptor in maintaining the integrity of the intestinal mucosal barrier
Juan Kong et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton
Andrea Hartsock et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2008)
Unique role of junctional adhesion molecule-A in maintaining mucosal homeostasis in inflammatory bowel disease
Stefania Vetrano et al.
GASTROENTEROLOGY (2008)
Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3
Karen M. Lammers et al.
GASTROENTEROLOGY (2008)
Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity
K. Gecse et al.
GUT (2008)
Secreted enteric antimicrobial activity localises to the mucus surface layer
U. Meyer-Hoffert et al.
GUT (2008)
Thickness and continuity of the adherent colonic mucus barrier in active and quiescent ulcerative colitis and Crohn's disease
V. Strugala et al.
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE (2008)
Changes in the expression of claudins in active ulcerative colitis
Tadayuki Oshima et al.
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2008)
Neutrophil-mediated activation of epithelial protease-activated receptors-1 and-2 regulates barrier function and transepithelial migration
Alex C. Chin et al.
JOURNAL OF IMMUNOLOGY (2008)
Protease signaling to G protein-coupled receptors: Implications for inflammation and pain
Camila Dale et al.
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2008)
Barrier dysfunction due to distinct defensin deficiencies in small intestinal and colonic Crohn's disease
J. Wehkamp et al.
MUCOSAL IMMUNOLOGY (2008)
Newly identified genetic risk variants for celiac disease related to the immune response
Karen A. Hunt et al.
NATURE GENETICS (2008)
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
Malin E. V. Johansson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis
Chad K. Heazlewood et al.
PLOS MEDICINE (2008)
Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis
M. C. Wapenaar et al.
GUT (2008)
Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-β
Louise Hjerrild Zeuthen et al.
IMMUNOLOGY (2008)
Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease
Tamara Matysiak-Budnik et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
JAM-A regulates permeability and inflammation in the intestine in vivo
Mike G. Laukoetter et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Probiotic Escherichia coli Nissle 1917 Inhibits Leaky Gut by Enhancing Mucosal Integrity
Sya N. Ukena et al.
PLOS ONE (2007)
Secretory IgA mediates bacterial translocation to dendritic cells in mouse Peyer's patches with restriction to mucosal compartment
Khalil A. Kadaoui et al.
JOURNAL OF IMMUNOLOGY (2007)
DMBT1 confers mucosal protection in vivo and a deletion variant is associated with Crohn's disease
Marcus Renner et al.
GASTROENTEROLOGY (2007)
The safety, tolerance, pharmacokinetic and pharmacodynamic effects of single doses of AT-1001 in coeliac disease subjects: a proof of concept study
B. M. Paterson et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2007)
Combination enzyme therapy for gastric digestion of dietary gluten in patients with celiac sprue
Jonathan Gass et al.
GASTROENTEROLOGY (2007)
Tight junction proteins in gallbladder epithelium:: Different expression in acute acalculous and calculous cholecystitis
Joao J. Laurila et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2007)
IL-1β causes an increase in intestinal epithelial tight junction permeability
Rana M. Al-Sadi et al.
JOURNAL OF IMMUNOLOGY (2007)
Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury
Monica Froicu et al.
BMC IMMUNOLOGY (2007)
Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarization
Junichi Ikenouchi et al.
JOURNAL OF CELL BIOLOGY (2007)
Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome
Giovanni Barbara et al.
GASTROENTEROLOGY (2007)
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease
S. Zeissig et al.
GUT (2007)
Growth factor-like activity of gliadin, an alimentary protein: implications for coeliac disease
Maria Vittoria Barone et al.
GUT (2007)
Smoking and inflammatory bowel disease: A meta-analysis
Suhal S. Mahid et al.
MAYO CLINIC PROCEEDINGS (2006)
Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: A longitudinal study
Lars C. Stene et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2006)
Alterations in intestinal permeability
M. C. Arrieta et al.
GUT (2006)
ZO-1 and ZO-2 independently determine where claudins are polymerized in tight-junction strand formation
Kazuaki Umeda et al.
CELL (2006)
Differential expression and subcellular localization of claudin-7,-8,-12,-13, and-15 along the mouse intestine
Hiroki Fujita et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2006)
Transglutaminase-independent binding of gliadin to intestinal brush border membrane and GM1 ganglioside
Armin Alaedini et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
Neutrophil serine proteases: specific regulators of inflammation
Christine T. N. Pham
NATURE REVIEWS IMMUNOLOGY (2006)
Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives
A Sapone et al.
DIABETES (2006)
Differences in expression patterns of the tight junction proteins, claudin 1, 3, 4 and 5, in human ovarian surface epithelium as compared to epithelia in inclusion cysts and epithelial ovarian tumours
YH Zhu et al.
INTERNATIONAL JOURNAL OF CANCER (2006)
Down-regulation of the claudin-18 gene, identified through serial analysis of gene expression data analysis, in gastric cancer with an intestinal phenotype
Y Sanada et al.
JOURNAL OF PATHOLOGY (2006)
Enterocyte TLR4 mediates phagocytosis and translocation of bacteria across the intestinal barrier
Matthew D. Neal et al.
JOURNAL OF IMMUNOLOGY (2006)
Gliadin, zonulin and gut permeability: Effects on celiac and non- celiac intestinal mucosa and intestinal cell lines
S Drago et al.
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY (2006)
Genetic basis for increased intestinal permeability in families with Crohn's disease:: role of CARD15 3020insC mutation?
S Buhner et al.
GUT (2006)
Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease
SA Blair et al.
LABORATORY INVESTIGATION (2006)
The gastrointestinal tract stem cell niche
Tzung-Hai Yen et al.
STEM CELL REVIEWS (2006)
Functional gastrointestinal disorders and mast cells: implications for therapy
G Barbara et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2006)
Cytoskeleton reorganization and ultrastructural damage induced by gliadin in a three-dimensional in vitro model
Ersilia Dolfini et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2005)
Novel effects of the prototype translocating Escherichia coli, strain C25 on intestinal epithelial structure and barrier function
M Zareie et al.
CELLULAR MICROBIOLOGY (2005)
Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect
AJ Monsuur et al.
NATURE GENETICS (2005)
Bacterial population analysis of human colon and terminal ileum biopsies with 16S rRNA-based fluorescent probes: Commensal bacteria live in suspension and have no direct contact with epithelial cells
LA van der Waaij et al.
INFLAMMATORY BOWEL DISEASES (2005)
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells
S Prasad et al.
LABORATORY INVESTIGATION (2005)
Contribution of claudin-5 to barrier properties in tight junctions of epithelial cells
S Amasheh et al.
CELL AND TISSUE RESEARCH (2005)
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
M Rimoldi et al.
NATURE IMMUNOLOGY (2005)
Intracellular trafficking of CD23:: Differential regulation in humans and mice by both extracellular and intracellular exons
G Montagnac et al.
JOURNAL OF IMMUNOLOGY (2005)
The JAM family of proteins
KJ Mandell et al.
ADVANCED DRUG DELIVERY REVIEWS (2005)
Host-bacterial mutualism in the human intestine
F Bäckhed et al.
SCIENCE (2005)
Differential role for CD23 splice forms in apical to basolateral transcytosis of IgE/allergen complexes
G Montagnac et al.
TRAFFIC (2005)
Interferon-γ and tumor necrosis factor-α synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
FJ Wang et al.
AMERICAN JOURNAL OF PATHOLOGY (2005)
Caveolae: Stable membrane domains with a potential for internalization
AM Hommelgaard et al.
TRAFFIC (2005)
Targeting of secretory IgA to Peyer's patch dendritic and T cells after transport by intestinal M cells
J Rey et al.
JOURNAL OF IMMUNOLOGY (2004)
Effects of enteral supplementation with glutamine granules on intestinal mucosal barrier function in severe burned patients
X Peng et al.
BURNS (2004)
Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome
G Barbara et al.
GASTROENTEROLOGY (2004)
Expression and function of tight junctions in the crypt epithelium of human palatine tonsils
M Go et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2004)
Expression of claudin-7 and-8 along the mouse nephron
WY Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2004)
Food allergens are protected from degradation during CD23-mediated transepithelial transport
C Bevilacqua et al.
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY (2004)
Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms
M Bruewer et al.
JOURNAL OF IMMUNOLOGY (2003)
The effect of supplemental enteral glutamine on plasma levels, gut function, and outcome in severe burns: A randomized, double-blind, controlled clinical trial
YP Zhou et al.
JOURNAL OF PARENTERAL AND ENTERAL NUTRITION (2003)
Inducible and constitutive β-defensins are differentially expressed in Crohn's disease and ulcerative colitis
J Wehkamp et al.
INFLAMMATORY BOWEL DISEASES (2003)
Transcytosis: Crossing cellular barriers
PL Tuma et al.
PHYSIOLOGICAL REVIEWS (2003)
Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme
H Wolburg et al.
ACTA NEUROPATHOLOGICA (2003)
Size-selective loosening of the blood-brain barrier in claudin-5-deficient mice
T Nitta et al.
JOURNAL OF CELL BIOLOGY (2003)
TNF-α and IFN-γ regulate the expression of the NOD2 (CARD15) gene in human intestinal epithelial cells
P Rosenstiel et al.
GASTROENTEROLOGY (2003)
Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection
SE Girardin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Regulated portals of entry into the cell
SD Conner et al.
NATURE (2003)
Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation
J Berkes et al.
GUT (2003)
Host recognition of bacterial muramyl dipeptide mediated through NOD2
N Inohara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function
MG Clemente et al.
GUT (2003)
Isolation and functional characterization of the actin-binding region in the tight junction protein ZO-1
AS Fanning et al.
FASEB JOURNAL (2002)
The renal segmental distribution of claudins changes with development
JL Reyes et al.
KIDNEY INTERNATIONAL (2002)
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
Y Zolotarevsky et al.
GASTROENTEROLOGY (2002)
The first large population based twin study of coeliac disease
L Greco et al.
GUT (2002)
Mucosal flora in inflammatory bowel disease
A Swidsinski et al.
GASTROENTEROLOGY (2002)
Immunohistochemical analysis of ZO-1 in the duodenal mucosa of patients with untreated and treated celiac disease
M Montalto et al.
DIGESTION (2002)
Neutrophil transmigration in inflammatory bowel disease is associated with differential expression of epithelial intercellular junction proteins
T Kucharzik et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Mucin gene expression in intestinal epithelial cells in Crohn's disease
MP Buisine et al.
GUT (2001)
Claudin-6: A novel tight junction molecule is developmentally regulated in mouse embryonic epithelium
K Turksen et al.
DEVELOPMENTAL DYNAMICS (2001)
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
JP Hugot et al.
NATURE (2001)
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
F Hayashi et al.
NATURE (2001)
Molecular analysis of commensal host-microbial relations hips in the intestine
LV Hooper et al.
SCIENCE (2001)
Heterogeneity in expression and subcellular localization of claudins 2, 3, 4, and 5 in the rat liver, pancreas, and gut
C Rahner et al.
GASTROENTEROLOGY (2001)
Interferon-gamma and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function
T Oshima et al.
MICROVASCULAR RESEARCH (2001)
Induction of apoptosis in Caco-2 cells by wheat gliadin peptides
C Giovannini et al.
TOXICOLOGY (2000)
Phylogenetic relationships of butyrate-producing bacteria from the human gut
A Barcenilla et al.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2000)
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