期刊
FRONTIERS IN NUTRITION
卷 8, 期 -, 页码 -出版社
FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2021.731356
关键词
caloric restriction; frailty; older adults; sarcopenia; lifespan
资金
- Beijing Natural Science Foundation [7202059]
- Beijing Municipal Health Commission [Jing2019-2]
Frailty is an age-related clinical syndrome that can increase the risks of falls, disability, hospitalization, and death in older adults. Caloric restriction (CR) may help prevent frailty, but further research is needed to determine the specific mechanisms and CR regimens suitable for human use.
Frailty is an age-related clinical syndrome that may increase the risk of falls, disability, hospitalization, and death in older adults. Delaying the progression of frailty helps improve the quality of life in older adults. Caloric restriction (CR) may extend lifespan and reduce the risk of age-related diseases. However, few studies have explored the relationship between CR and frailty. In this review, we focused on the impact of CR on frailty and aimed to identify potential associated mechanisms. Although CR may help prevent frailty, further studies are required to determine the underlying mechanisms and specific CR regimens suitable for use in humans.
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