4.8 Article

Efficient pyrido[1,2-a]benzimidazole formation from 2-aminopyridines and cyclohexanones under metal-free conditions

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GREEN CHEMISTRY
卷 18, 期 3, 页码 667-671

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c5gc01978h

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资金

  1. National Natural Science Foundation of China [21572194, 21372187]
  2. Research Fund for the Doctoral Program of Higher Education of China
  3. Ministry of Education of China [20124301110005]
  4. Hunan Provincial Innovative Foundation for Postgraduates [CX2015B202]

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An efficient procedure for pyrido[1,2-a]benzimidazole preparation from 2-aminopyridines and cyclohexanones under metal-free conditions is described. Non-aromatic cyclohexanones were used as the aryl source via a dehydrogenation-aromatization process using molecular oxygen as the green oxidant.

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