4.6 Article

DCLK1 isoforms and aberrant Notch signaling in the regulation of human and murine colitis

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Summary: Notch signaling pathway plays a crucial role in regulating cellular differentiation and function in the innate and adaptive immune systems of mammals. It is essential for T cell lineage development and function, as well as for B cell development and maintenance. Notch signaling also has emerging roles in innate and innate-like cell lineages.

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