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New quinazoline derivatives for telomeric G-quadruplex DNA: Effects of an added phenyl group on quadruplex binding ability
Jin-Hui He et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
Structure-Based Design and Evaluation of Naphthalene Diimide G-Quadruplex Ligands As Telomere Targeting Agents in Pancreatic Cancer Cells
Marialuisa Micco et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Study on effects of molecular crowding on G-quadruplex-ligand binding and ligand-mediated telomerase inhibition
Hidenobu Yaku et al.
METHODS (2013)
The crystal structure of human telomeric DNA complexed with berberine: an interesting case of stacked ligand to G-tetrad ratio higher than 1:1
Carla Bazzicalupi et al.
NUCLEIC ACIDS RESEARCH (2013)
G4LDB: a database for discovering and studying G-quadruplex ligands
Qian Li et al.
NUCLEIC ACIDS RESEARCH (2013)
Correction: Structure and Stability of Human Telomeric G-Quadruplex with Preclinical 9-Amino Acridines
Ruben Ferreira et al.
PLoS One (2013)
Selective RNA Versus DNA G-Quadruplex Targeting by In Situ Click Chemistry
Marco Di Antonio et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Circular Dichroism Spectroscopy of DNA: From Duplexes to Quadruplexes
Michaela Vorlickova et al.
CHIRALITY (2012)
Heterocyclic Dications as a New Class of Telomeric G-Quadruplex Targeting Agents
Rupesh Nanjunda et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Experimental Methods for Studying the Interactions between G-Quadruplex Structures and Ligands
Joaquim Jaumot et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Selective isolation of G-quadruplexes by affinity chromatography
Tianjun Chang et al.
JOURNAL OF CHROMATOGRAPHY A (2012)
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
Raphael Rodriguez et al.
NATURE CHEMICAL BIOLOGY (2012)
The porphyrin TmPyP4 unfolds the extremely stable G-quadruplex in MT3-MMP mRNA and alleviates its repressive effect to enhance translation in eukaryotic cells
Mark J. Morris et al.
NUCLEIC ACIDS RESEARCH (2012)
Development of a high-throughput G4-FID assay for screening and evaluation of small molecules binding quadruplex nucleic acid structures
Eric Largy et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2011)
An Acyclic Oligoheteroaryle That Discriminates Strongly between Diverse G-Quadruplex Topologies
Florian Hamon et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)
Fluorescence intercalator displacement assay for screening G4 ligands towards a variety of G-quadruplex structures
Phong Lan Thao Tran et al.
BIOCHIMIE (2011)
Efficient Suppression of Gene Expression by Targeting 5′-UTR-Based RNA Quadruplexes with Bisquinolinium Compounds
Kangkan Halder et al.
CHEMBIOCHEM (2011)
Methods for investigating G-quadruplex DNA/ligand interactions
Pierre Murat et al.
CHEMICAL SOCIETY REVIEWS (2011)
MASS SPECTROMETRY OF G-QUADRUPLEX DNA: FORMATION, RECOGNITION, PROPERTY, CONVERSION, AND CONFORMATION
Gu Yuan et al.
MASS SPECTROMETRY REVIEWS (2011)
Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
Shankar Balasubramanian et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
Light-driven conformational regulation of human telomeric G-quadruplex DNA in physiological conditions
Xiwen Xing et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2011)
Human telomeric G-quadruplex: The current status of telomeric G-quadruplexes as therapeutic targets in human cancer
Stephen Neidle
FEBS JOURNAL (2010)
Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis
Denis Drygin et al.
CANCER RESEARCH (2009)
Applications of Isothermal Titration Calorimetry in Biophysical Studies of G-quadruplexes
Bruno Pagano et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2009)
Shedding Light on the Interaction between TMPyP4 and Human Telomeric Quadruplexes
Luigi Martino et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2009)
The quadruplex r(CGG)n destabilizing cationic porphyrin TMPyP4 cooperates with hnRNPs to increase the translation efficiency of fragile X premutation mRNA
Noa Ofer et al.
NUCLEIC ACIDS RESEARCH (2009)
Ligands playing musical chairs with G-quadruplex DNA: A rapid and simple displacement assay for identifying selective G-quadruplex binders
D. Monchaud et al.
BIOCHIMIE (2008)
Circular dichroism to determine binding mode and affinity of ligand-DNA interactions
Nichola C. Garbett et al.
NATURE PROTOCOLS (2007)
G-quadruplexes in promoters throughout the human genome
Julian L. Huppert et al.
NUCLEIC ACIDS RESEARCH (2007)
Ligand-driven G-quadruplex conformational switching by using an unusual mode of interaction
Raphael Rodriguez et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Quadruplex DNA: sequence, topology and structure
Sarah Burge et al.
NUCLEIC ACIDS RESEARCH (2006)
Development of a fluorescent intercalator displacement assay (G4-FID) for establishing quadruplex-DNA affinity and selectivity of putative ligands
David Monchaud et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
The G-quadruplex-interactive molecule BRACO-19 inhibits tumor growth, consistent with telomere targeting and interference with telomerase function
AM Burger et al.
CANCER RESEARCH (2005)
Prevalence of quadruplexes in the human genome
JL Huppert et al.
NUCLEIC ACIDS RESEARCH (2005)
Drug recognition and stabilisation of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human telomeric repeat
E Gavathiotis et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Selective interaction of ethidium derivatives with quadruplexes: An equilibrium dialysis and electrospray ionization mass spectrometry analysis
F Rosu et al.
BIOCHEMISTRY (2003)
Structure of the first parallel DNA quadruplex-drug complex
GR Clark et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Structure of a G-quadruplex-ligand complex
SM Haider et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
Structure-based design of selective and potent G quadruplex-mediated telomerase inhibitors
M Read et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Telomestatin, a novel telomerase inhibitor from Streptomyces anulatus
K Shin-ya et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
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