4.6 Article

Efficacy of an Anti-Cellulite Herbal Emgel: A Randomized Clinical Trial

期刊

PHARMACEUTICALS
卷 14, 期 7, 页码 -

出版社

MDPI
DOI: 10.3390/ph14070683

关键词

anti cellulite; herbal compress; herbal emgel; essential oils; clinical trial

资金

  1. Royal Golden Jubilee Program (RGJ-PhD) [0008/2560]
  2. Thailand Center of Excellence for Life Sciences (TCEL) [TC-A2/62]
  3. National Research Council of Thailand (NRCT) [DBG6080005, IRN61W0005]
  4. Center of Excellence for Innovation in Chemistry (PERCH-CIC)
  5. Ministry of Higher Education, Science, Research and Innovation

向作者/读者索取更多资源

A herbal 'emgel' containing extracts of a traditional Thai herbal compress was tested on women with severe cellulite, showing improvement in the appearance of cellulite and safety in use. Further studies on active constituents and mechanisms of action are needed for future exploration.
Cellulite describes unsightly skin overlying subcutaneous fat around thighs and buttocks of post-pubescent females. A herbal 'emgel' containing volatile oils and extracts of A traditional Thai herbal compress was tested in a double-blind, placebo-controlled trial with 18 women aged 20-50 year with severe cellulite. Appearance of cellulite (primary outcome), thigh circumferences, skin firmness, and cutaneous blood flow (secondary outcomes) were assessed at baseline, 2, 4, 8 and 12 weeks with a 2-week follow-up. Herbal emgel applied onto the thigh skin twice daily reduced cellulite severity scores in every time point. The score was reduced from 13.4 +/- 0.3 (baseline) to 12.1 +/- 0.3 (week 2) and 9.9 +/- 0.6 (week 12). All secondary outcomes improved with both placebo and herbal emgels suggesting that ingredients in the base-formulation might be responsible. Querying of participants, analysis of their diaries, and physical monthly inspections found no adverse events. The herbal emgel safely improved the appearance of cellulite, while the base emgel may play a role for other endpoints. Further studies on the active constituents and their mechanism of action are needed to further explore these factors.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据