相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Characterisation of a novel thrombomodulin c.1487delC,p. (Pro496Argfs*10) variant and evaluation of therapeutic strategies to manage the rare bleeding phenotype
Gael B. Morrow et al.
THROMBOSIS RESEARCH (2021)
The mutational constraint spectrum quantified from variation in 141,456 humans
Konrad J. Karczewski et al.
NATURE (2020)
A case of thrombomodulin mutation causing defective thrombin binding with absence of protein C and TAFI activation
Masahiko Okada et al.
BLOOD ADVANCES (2020)
Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy The SCARLET Randomized Clinical Trial
Jean-Louis Vincent et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2019)
Thrombomodulin in disseminated intravascular coagulation and other critical conditions-a multi-faceted anticoagulant protein with therapeutic potential
Takashi Ito et al.
CRITICAL CARE (2019)
Exploring traditional and nontraditional roles for thrombomodulin
Houra Loghmani et al.
BLOOD (2018)
Thrombomodulin and Endothelial Dysfunction: A Disease-Modifier Shared between Malignant Hypertension and Atypical Hemolytic Uremic Syndrome
Marieke Demeulenaere et al.
NEPHRON (2018)
Variable phenotypic penetrance of thrombosis in adult mice after tissue-selective and temporally controlled Thbd gene inactivation
Thijs E. van Mens et al.
BLOOD ADVANCES (2017)
Thrombomodulin as an intravascular safeguard against inflammatory and thrombotic diseases
Takashi Ito et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2016)
A hereditary bleeding disorder resulting from a premature stop codon in thrombomodulin (p.Cys537Stop)
Jonathan Langdown et al.
BLOOD (2014)
Protein C anticoagulant and cytoprotective pathways
John H. Griffin et al.
INTERNATIONAL JOURNAL OF HEMATOLOGY (2012)
Intraovarian Thrombin and Activated Protein C Signaling System Regulates Steroidogenesis during the Periovulatory Period
Yuan Cheng et al.
MOLECULAR ENDOCRINOLOGY (2012)
Thrombomodulin Mutations in Atypical Hemolytic-Uremic Syndrome
Mieke Delvaeye et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The thrombomodulin-protein C system is essential for the maintenance of pregnancy
B Isermann et al.
NATURE MEDICINE (2003)
Characterization of a mouse model for thrombomodulin deficiency
H Weiler et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2001)
Endothelium-specific loss of murine thrombomodulin disrupts the protein C anticoagulant pathway and causes juvenile-onset thrombosis
B Isermann et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
Elements of the primary structure of thrombomodulin required for efficient thrombin-activable fibrinolysis inhibitor activation
W Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex
P Fuentes-Prior et al.
NATURE (2000)