期刊
JOURNAL OF FUNGI
卷 7, 期 9, 页码 -出版社
MDPI
DOI: 10.3390/jof7090715
关键词
DC corona discharge; Microsporum; treatment of mycoses; Trichophyton
资金
- Charles University [Progress Q25]
The study revealed that sensitivity to non-thermal plasma is not a fixed characteristic of fungal species, but varies among different strains. Significant differences were observed in the inactivation dynamics of various dermatophytes exposed to plasma, indicating that sensitivity is strain-specific rather than species-specific.
Following our previous study of the therapy of onychomycosis by non-thermal plasma (NTP) and nail hygiene and to obtain some prerequisite data of dermatophytes sensitivity, the dynamics of those inactivation by NTP plasma was monitored for various strains of Trichophyton iterdigitale, Trichophyton benhamiae, Trichophyton rubrum, and Microsporum canis. Three strains of each species on agar plates were exposed with plasma produced by a DC corona discharge in the point-to-ring arrangement in various time intervals. Although all strains were sufficiently sensitive to plasma action, significant differences were observed in their sensitivity and inactivation dynamics. These differences did not correlate with the species classification of individual strains, but could be assigned to four arbitrarily created types of strain response to NTP according to their sensitivity. These results indicate that the sensitivity to plasma is not an inherent property of the fungal species, but varies from strain to strain.
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