相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Parkinson disease
R. Balestrino et al.
EUROPEAN JOURNAL OF NEUROLOGY (2020)
LRRK2 in Parkinson disease: challenges of clinical trials
Eduardo Tolosa et al.
NATURE REVIEWS NEUROLOGY (2020)
Structure of LRRK2 in Parkinson's disease and model for microtubule interaction
C. K. Deniston et al.
NATURE (2020)
CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons
Carles Calatayud et al.
SCIENTIFIC REPORTS (2019)
Enhancing glycolysis attenuates Parkinson's disease progression in models and clinical databases
Rong Cai et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
InterPro in 2019: improving coverage, classification and access to protein sequence annotations
Alex L. Mitchell et al.
NUCLEIC ACIDS RESEARCH (2019)
Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease
Angelique di Domenico et al.
STEM CELL REPORTS (2019)
WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research
Denise N. Slenter et al.
NUCLEIC ACIDS RESEARCH (2018)
The Reactome Pathway Knowledgebase
Antonio Fabregat et al.
NUCLEIC ACIDS RESEARCH (2018)
LRRK2 activation in idiopathic Parkinson's disease
Roberto Di Maio et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Impact of modular organization on dynamical richness in cortical networks
Hideaki Yamamoto et al.
SCIENCE ADVANCES (2018)
Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease
Amy R. Dunn et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Distinct Role of Striatal Functional Connectivity and Dopaminergic Loss in Parkinson's Symptoms
Juergen Dukart et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
Parkinson disease
Werner Poewe et al.
NATURE REVIEWS DISEASE PRIMERS (2017)
Abnormal intrinsic brain functional network dynamics in Parkinson's disease
Jinhee Kim et al.
BRAIN (2017)
Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
Ivan Carcamo-Orive et al.
CELL STEM CELL (2017)
Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through activating the Akt/Nrf pathway and inhibiting GSK3β activity
Chin-Hsien Lin et al.
HUMAN MOLECULAR GENETICS (2016)
Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation
Bridget A. Matikainen-Ankney et al.
JOURNAL OF NEUROSCIENCE (2016)
Neuronal networks provide rapid neuroprotection against spreading toxicity
Andrew J. Samson et al.
SCIENTIFIC REPORTS (2016)
Neuronal hyperactivity - A key defect in Alzheimer's disease?
Marc Aurel Busche et al.
BIOESSAYS (2015)
Development and function of human cerebral cortex neural networks from pluripotent stem cells in vitro
Peter Kirwan et al.
DEVELOPMENT (2015)
Cellular processes associated with LRRK2 function and dysfunction
Rebecca Wallings et al.
FEBS JOURNAL (2015)
limma powers differential expression analyses for RNA-sequencing and microarray studies
Matthew E. Ritchie et al.
NUCLEIC ACIDS RESEARCH (2015)
Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability
Anna-Claire Devlin et al.
NATURE COMMUNICATIONS (2015)
Activity and High-Order Effective Connectivity Alterations in Sanfilippo C Patient-Specific Neuronal Networks
Isaac Canals et al.
STEM CELL REPORTS (2015)
Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation
Andrew J. Schwab et al.
STEM CELL REPORTS (2015)
Altered Resting-State Brain Activity and Connectivity in Depressed Parkinson's Disease
Xiao Hu et al.
PLOS ONE (2015)
Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer's Disease
Zuzana Siskova et al.
NEURON (2014)
Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
Peter Reinhardt et al.
CELL STEM CELL (2013)
Interplay of LRRK2 with chaperone-mediated autophagy
Samantha J. Orenstein et al.
NATURE NEUROSCIENCE (2013)
Noise focusing and the emergence of coherent activity in neuronal cultures
Javier G. Orlandi et al.
NATURE PHYSICS (2013)
Genome engineering using the CRISPR-Cas9 system
F. Ann Ran et al.
NATURE PROTOCOLS (2013)
Identification of neuronal network properties from the spectral analysis of calcium imaging signals in neuronal cultures
Elisenda Tibau et al.
FRONTIERS IN NEURAL CIRCUITS (2013)
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease
Adriana Sanchez-Danes et al.
EMBO MOLECULAR MEDICINE (2012)
Interregional Correlations in Parkinson Disease and Parkinson-related Dementia with Resting Functional MR Imaging
Tyler M. Seibert et al.
RADIOLOGY (2012)
Generation of Regionally Specified Neural Progenitors and Functional Neurons from Human Embryonic Stem Cells under Defined Conditions
Agnete Kirkeby et al.
CELL REPORTS (2012)
Model-Free Reconstruction of Excitatory Neuronal Connectivity from Calcium Imaging Signals
Olav Stetter et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
Molecular signatures database (MSigDB) 3.0
Arthur Liberzon et al.
BIOINFORMATICS (2011)
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
Sonja Kriks et al.
NATURE (2011)
Genomic safe harbors permit high beta-globin transgene expression in thalassemia induced pluripotent stem cells
Eirini P. Papapetrou et al.
NATURE BIOTECHNOLOGY (2011)
Functional multineuron calcium imaging for systems pharmacology
Naoya Takahashi et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2010)
Clinical Progression in Parkinson Disease and the Neurobiology of Axons
Hsiao-Chun Cheng et al.
ANNALS OF NEUROLOGY (2010)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
Complex network measures of brain connectivity: Uses and interpretations
Mikail Rubinov et al.
NEUROIMAGE (2010)
The NCBI BioSystems database
Lewis Y. Geer et al.
NUCLEIC ACIDS RESEARCH (2010)
Lentiviral Vectors and Protocols for Creation of Stable hESC Lines for Fluorescent Tracking and Drug Resistance Selection of Cardiomyocytes
Hiroko Kita-Matsuo et al.
PLOS ONE (2009)
Maximization of the connectivity repertoire as a statistical principle governing the shapes of dendritic arbors
Quan Wen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Development of input connections in neural cultures
Jordi Soriano et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-Linking familial and sporadic Parkinson's disease
Vincenzo Bonifati
NEUROCHEMICAL RESEARCH (2007)
A systems biology approach for pathway level analysis
Sorin Draghici et al.
GENOME RESEARCH (2007)
Watching neuronal circuit dynamics through functional multineuron calcium imaging (fMCI)
Naoya Takahashi et al.
NEUROSCIENCE RESEARCH (2007)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Cellular and network mechanisms of slow oscillatory activity (<1 Hz) and wave propagations in a cortical network model
A Compte et al.
JOURNAL OF NEUROPHYSIOLOGY (2003)