Case Report: Tropheryma whipplei Hide in an AIDS Patient With Pneumocystis Pneumonia

Introduction: Pneumocystis pneumonia (PCP) is one of the most common opportunistic infections in HIV-infected patients. However, coinfection with Tropheryma whipplei is infrequent in AIDS patients with PCP. Case Presentation: We report a 28-year-old male AIDS patient coinfected with T. whipplei and Pneumocystis jirovecii diagnosed in the bronchoalveolar lavage. After sulfamethoxazole-trimethoprim and meropenem treatment, the patient showed clinical improvement in 2 weeks. Conclusion: Clinicians need to be alert to the occurrence of T. whipplei infection in AIDS patients with PCP and timely diagnosis and antibacterial treatments are essential. This case may help clinicians for timely diagnosis of the coinfection of T. whipplei and P. jirovecii in AIDS patients.

Automated summary

This case report describes a 28-year-old male AIDS patient coinfected with T. whipplei and Pneumocystis jirovecii, showing significant clinical improvement after 2 weeks of treatment. It highlights the importance of clinicians being vigilant for T. whipplei infection in AIDS patients, and the necessity of timely diagnosis and antibacterial treatments.