期刊
DIAGNOSTICS
卷 11, 期 8, 页码 -出版社
MDPI
DOI: 10.3390/diagnostics11081427
关键词
gallbladder; cancer; diagnosis; fine needle aspiration cytology
Gallbladder cancer is the most common malignancy of the biliary tract, and early diagnosis and assessment are crucial for improving survival rates. Fine needle aspiration cytology has high sensitivity and specificity in the management of gallbladder cancer, suggesting that suspicious masses should be further evaluated with FNAC for appropriate management.
Gallbladder cancer is the most common malignancy of the biliary tract. When diagnosed in an advanced stage it has a very poor prognosis. Therefore, early diagnosis and thorough assessment of a suspicious gallbladder polyp is essential to improve survival rate. The aim of this systematic review is to assess the role of fine needle aspiration cytology (FNAC) in the management of gallbladder cancer. For that purpose, a systematic review was carried out in the MEDLINE, EMBASE, Cochrane, Scopus and Google Scholar databases between 1 July 2004 and 22 April 2021. Six studies with 283 patients in total were included. Pooled sensitivity and specificity of FNAC were 0.85 and 0.94, respectively, while the area under the calculated summary receiver operating characteristic (SROC curve (AUC) was 0.98. No complications were reported. Based on the high diagnostic performance of FNAC in the assessment of gallbladder masses, we suggest that every suspicious mass should be evaluated further with FNAC to facilitate the most appropriate management.
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