期刊
DIAGNOSTICS
卷 11, 期 7, 页码 -出版社
MDPI
DOI: 10.3390/diagnostics11071285
关键词
biomarkers; biosensors; body fluids; optical detections; point-of-care; diagnostics; devices
资金
- Australia-China Science and Research Fund
- Joint Research Centre for Personal Health Technologies
The focus of researchers in recent years has been on integrating point-of-care strategies into biomarker detection, with optical-based detection methods and emerging AIEgens playing a key role in portable medical devices. Various optical measurements, including colorimetry, fluorescence, and chemiluminescence, are compared in POC systems for detecting and monitoring biomarkers in bodily fluids. The potential of using optical detection-based portable devices in future healthcare activities is also explored.
The detection and monitoring of biomarkers in body fluids has been used to improve human healthcare activities for decades. In recent years, researchers have focused their attention on applying the point-of-care (POC) strategies into biomarker detection. The evolution of mobile technologies has allowed researchers to develop numerous portable medical devices that aim to deliver comparable results to clinical measurements. Among these, optical-based detection methods have been considered as one of the common and efficient ways to detect and monitor the presence of biomarkers in bodily fluids, and emerging aggregation-induced emission luminogens (AIEgens) with their distinct features are merging with portable medical devices. In this review, the detection methodologies that use optical measurements in the POC systems for the detection and monitoring of biomarkers in bodily fluids are compared, including colorimetry, fluorescence and chemiluminescence measurements. The current portable technologies, with or without the use of smartphones in device development, that are combined with optical biosensors for the detection and monitoring of biomarkers in body fluids, are also investigated. The review also discusses novel AIEgens used in the portable systems for the detection and monitoring of biomarkers in body fluid. Finally, the potential of future developments and the use of optical detection-based portable devices in healthcare activities are explored.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据