相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。High eosinophil counts predict decline in FEV1: results from the CanCOLD study
Wan C. Tan et al.
EUROPEAN RESPIRATORY JOURNAL (2021)
Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment
Natalie M. Niessen et al.
ALLERGY (2021)
Neutrophils in asthma: the good, the bad and the bacteria
Helena Crisford et al.
THORAX (2021)
Beclometasone dipropionate/formoterol maintenance and reliever therapy asthma exacerbation benefit increases with blood eosinophil level
Guy Brusselle et al.
EUROPEAN RESPIRATORY JOURNAL (2021)
A Comprehensive Analysis of the Stability of Blood Eosinophil Levels
Bradley E. Chipps et al.
ANNALS OF THE AMERICAN THORACIC SOCIETY (2021)
Mechanisms and therapeutic strategies for non-T2 asthma
Eric Sze et al.
ALLERGY (2020)
Dupilumab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Allergic Asthma
Jonathan Corren et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2020)
Predictive factors of response to inhaled corticosteroids in newly diagnosed asthma A real-world observational study
Hyo-In Rhyou et al.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY (2020)
Anti-IL5 Therapies for Severe Eosinophilic Asthma: Literature Review and Practical Insights
Francesco Menzella et al.
JOURNAL OF ASTHMA AND ALLERGY (2020)
The Airway Epithelium-A Central Player in Asthma Pathogenesis
Jenny Calven et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Annual Fractional Exhaled Nitric Oxide Measurements and Exacerbations in Severe Asthma
Yuki Abe et al.
JOURNAL OF ASTHMA AND ALLERGY (2020)
The effects of oral corticosteroids on lung function, type-2 biomarkers and patient-reported outcomes in stable asthma: A systematic review and meta-analysis
John Busby et al.
RESPIRATORY MEDICINE (2020)
Serum periostin levels serve as a biomarker for both eosinophilic airway inflammation and fixed airflow limitation in well-controlled asthmatics
Kentaro Takahashi et al.
JOURNAL OF ASTHMA (2019)
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019
Dave Singh et al.
EUROPEAN RESPIRATORY JOURNAL (2019)
Periostin: An emerging biomarker for allergic diseases
Kenji Izuhara et al.
ALLERGY (2019)
Change in type-2 biomarkers and related cytokines with prednisolone in uncontrolled severe oral corticosteroid dependent asthmatics: an interventional open-label study
John Busby et al.
THORAX (2019)
Eosinophil-guided corticosteroid therapy in patients admitted to hospital with COPD exacerbation (CORTICO-COP): a multicentre, randomised, controlled, open-label, non-inferiority trial
Pradeesh Sivapalan et al.
LANCET RESPIRATORY MEDICINE (2019)
Neutrophilic asthma: welcome back!
Peter G. Gibson et al.
EUROPEAN RESPIRATORY JOURNAL (2019)
Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze
Polly F. M. Robinson et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)
Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients
Patrizia Pignatti et al.
RESPIRATORY RESEARCH (2019)
Long-Term Triple Therapy De-escalation to Indacaterol/Glycopyrronium in Patients with Chronic Obstructive Pulmonary Disease (SUNSET): A Randomized, Double-Blind, Triple-Dummy Clinical Trial
Kenneth R. Chapman et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)
Prospective predictors of exacerbation status in severe asthma over a 3-year follow-up
H. Kimura et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2018)
Human T Cell Development, Localization, and Function throughout Life
Brahma V. Kumar et al.
IMMUNITY (2018)
Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease
Jeong H. Yun et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)
Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology
Steven L. Taylor et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)
Effect of procalcitonin-guided antibiotic treatment on mortality in acute respiratory infections: a patient level meta-analysis
Philipp Schuetz et al.
LANCET INFECTIOUS DISEASES (2018)
Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD
David A. Lipson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Fractional exhaled nitric oxide as a predictor of response to inhaled corticosteroids in patients with non-specific respiratory symptoms and insignificant bronchodilator reversibility: a randomised controlled trial
David B. Price et al.
LANCET RESPIRATORY MEDICINE (2018)
Predictors of exacerbation risk and response to budesonide in patients with chronic obstructive pulmonary disease: a post-hoc analysis of three randomised trials
Mona Bafadhel et al.
LANCET RESPIRATORY MEDICINE (2018)
Predictors of enhanced response with benralizumab for patients with severe asthma: pooled analysis of the SIROCCO and CALIMA studies
J. Mark FitzGerald et al.
LANCET RESPIRATORY MEDICINE (2018)
Relationship of Blood Eosinophil Count to Exacerbations in Chronic Obstructive Pulmonary Disease
Robert S. Zeiger et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2018)
Disconnect of type 2 biomarkers in severe asthma; dominated by FeNO as a predictor of exacerbations and periostin as predictor of reduced lung function
Adel H. Mansur et al.
RESPIRATORY MEDICINE (2018)
Exhaled and nasal nitric oxide in chronic rhinosinusitis patients with nasal polyps in primary care
Martin Frendo et al.
RHINOLOGY (2018)
Clinical utility of fractional exhaled nitric oxide and blood eosinophils counts in the diagnosis of asthma-COPD overlap
Yusuke Takayama et al.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2018)
Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids
Salman H. Siddiqui et al.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2018)
Antibiotic resistance: a rundown of a global crisis
Bilal Aslam et al.
INFECTION AND DRUG RESISTANCE (2018)
Evaluation of Systemic Corticosteroids in Patients With an Acute Exacerbation of COPD and a Diagnosis of Pneumonia
Tyler Scholl et al.
CHRONIC OBSTRUCTIVE PULMONARY DISEASES-JOURNAL OF THE COPD FOUNDATION (2018)
Non-eosinophilic asthma: current perspectives
Ignacio Esteban-Gorgojo et al.
JOURNAL OF ASTHMA AND ALLERGY (2018)
FeNO-based asthma management results in faster improvement of airway hyperresponsiveness
Katrine Feldballe Bernholm et al.
ERJ OPEN RESEARCH (2018)
The clinical response to omalizumab in chronic spontaneous urticaria patients is linked to and predicted by IgE levels and their change
R. Ertas et al.
ALLERGY (2018)
Novel monoclonal treatments in severe asthma
Howraman Meteran et al.
JOURNAL OF ASTHMA (2017)
Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial
Peter G. Gibson et al.
LANCET (2017)
Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease
I. D. Pavord et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Effectiveness of inhaled corticosteroids in real life on clinical outcomes, sputum cells and systemic inflammation in asthmatics: a retrospective cohort study in a secondary care centre
Sophie F. Demarche et al.
BMJ OPEN (2017)
Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study
Akbar K. Waljee et al.
BMJ-BRITISH MEDICAL JOURNAL (2017)
Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study
Akbar K. Waljee et al.
BMJ-BRITISH MEDICAL JOURNAL (2017)
Association of sputum and blood eosinophil concentrations with clinical measures of COPD severity: an analysis of the SPIROMICS cohort
Annette T. Hastie et al.
LANCET RESPIRATORY MEDICINE (2017)
Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections
Philipp Schuetz et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)
Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults
Helen L. Petsky et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)
Eosinophilia, Frequent Exacerbations, and Steroid Response in Chronic Obstructive Pulmonary Disease
Peter M. A. Calverley et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Allergen-induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Subjects with Asthma
Ruchong Chen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Personalised medicine in asthma: time for action
Kian Fan Chung
EUROPEAN RESPIRATORY REVIEW (2017)
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report
Claus F. Vogelmeier et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Eosinophils in COPD Exacerbations Are Associated With Increased Readmissions
Simon Couillard et al.
CHEST (2017)
Effect of treatment with inhaled corticosteroid on serum periostin levels in asthma
Makoto Hoshino et al.
RESPIROLOGY (2016)
Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD
Ian D. Pavord et al.
THORAX (2016)
Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease
Leena George et al.
THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2016)
Blood Eosinophils and Exacerbations in Chronic Obstructive Pulmonary Disease The Copenhagen General Population Study
Signe Vedel-Krogh et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)
Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma Effects Across a Broad Range of Eosinophil Counts
Jonathan Corren et al.
CHEST (2016)
Blood Eosinophils and Outcomes in Severe Hospitalized Exacerbations of COPD
Mona Bafadhel et al.
CHEST (2016)
Reslizumab for Inadequately Controlled Asthma With Elevated Blood Eosinophil Levels A Randomized Phase 3 Study
Leif Bjermer et al.
CHEST (2016)
Response to Omalizumab Therapy Based on Level of IgE: A Two Year Observational Study (REALITY Study)
Jay Peters et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
Inflammatory mechanisms in patients with chronic obstructive pulmonary disease
Peter J. Barnes
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)
Benralizumab, an anti-interleukin-5 receptor a monoclonal antibody, as add-on treatment for patients with severe, uncontrolled, eosinophilic asthma (CALIMA): a randomised, double-blind, placebo-controlled phase 3 trial
J. Mark FitzGerald et al.
LANCET (2016)
Estimating National Trends in Inpatient Antibiotic Use Among US Hospitals From 2006 to 2012
James Baggs et al.
JAMA INTERNAL MEDICINE (2016)
Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD
Netsanet A. Negewo et al.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2016)
Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial
Henrik Watz et al.
LANCET RESPIRATORY MEDICINE (2016)
Severe eosinophilic asthma treated with mepolizumab stratified by baseline eosinophil thresholds: a secondary analysis of the DREAM and MENSA studies
Hector G. Ortega et al.
LANCET RESPIRATORY MEDICINE (2016)
Therapeutic implications of 'neutrophilic asthma'
Parameswaran Nair et al.
CURRENT OPINION IN PULMONARY MEDICINE (2015)
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort
Dominick E. Shaw et al.
EUROPEAN RESPIRATORY JOURNAL (2015)
The utility of inflammatory markers to predict readmissions and mortality in COPD cases with or without eosinophilia
Dildar Duman et al.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2015)
Reslizumab for inadequately controlled asthma with elevated blood eosinophil counts: results from two multicentre, parallel, double-blind, randomised, placebo-controlled, phase 3 trials
Mario Castro et al.
LANCET RESPIRATORY MEDICINE (2015)
Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial
Christopher E. Brightling et al.
LANCET RESPIRATORY MEDICINE (2015)
Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma
Joe K. Gerald et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2015)
External validation of blood eosinophils, FENO and serum periostin as surrogates for sputum eosinophils in asthma
A. H. Wagener et al.
THORAX (2015)
Effects of weight loss on asthma control in obese patients with severe asthma
Servulo Azevedo Dias-Junior et al.
EUROPEAN RESPIRATORY JOURNAL (2014)
Importance of concomitant local and systemic eosinophilia in uncontrolled asthma
Florence Nicole Schleich et al.
EUROPEAN RESPIRATORY JOURNAL (2014)
Outdoor air pollution and asthma
Michael Guarnieri et al.
LANCET (2014)
Withdrawal of Inhaled Glucocorticoids and Exacerbations of COPD
Helgo Magnussen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study
Christopher E. Brightling et al.
LANCET RESPIRATORY MEDICINE (2014)
Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease
Julia A. E. Walters et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2014)
Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease
Kayleigh M. Kew et al.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2014)
Procalcitonin guidance for reduction of antibiotic use in patients hospitalized with severe acute exacerbations of asthma: a randomized controlled study with 12-month follow-up
Wei Long et al.
CRITICAL CARE (2014)
Procalcitonin guided antibiotic therapy of acute exacerbations of asthma: a randomized controlled trial
Jianguo Tang et al.
BMC INFECTIOUS DISEASES (2013)
Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects
Annette T. Hastie et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)
Lysis of primed eosinophils in severe asthma
Carl Persson
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)
Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma
Juan-juan Fu et al.
OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2013)
Relationship between airway neutrophilia and ageing in asthmatics and non-asthmatics
Collin R. Brooks et al.
RESPIROLOGY (2013)
Obesity in asthma: more neutrophilic inflammation as a possible explanation for a reduced treatment response
E. D. Telenga et al.
ALLERGY (2012)
Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease A Randomized Placebo-Controlled Trial
Mona Bafadhel et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic
Kelly Wong McGrath et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Reduction of total IgE by targeted coengagement of IgE B-cell receptor and FcγRIIb with Fc-engineered antibody
Seung Y. Chu et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2012)
An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications
Raed A. Dweik et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgE
Philip J. Lowe et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2011)
Different inflammatory phenotypes in adults and children with acute asthma
F. Wang et al.
EUROPEAN RESPIRATORY JOURNAL (2011)
Management of asthma in pregnancy guided by measurement of fraction of exhaled nitric oxide: a double-blind, randomised controlled trial
Heather Powell et al.
LANCET (2011)
Lebrikizumab Treatment in Adults with Asthma
Jonathan Corren et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Lower FEV1 in non-COPD, nonasthmatic subjects: association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes
Hironori Masuko et al.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2011)
Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program
Wendy C. Moore et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)
Airway hyperresponsiveness to mannitol and methacholine and exhaled nitric oxide: A random-sample population study
Asger Sverrild et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
Eosinophil protein in airway macrophages: A novel biomarker of eosinophilic inflammation in patients with asthma
Neeta S. Kulkarni et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)
Innate Cells and T Helper 2 Cell Immunity in Airway Inflammation
Nora A. Barrett et al.
IMMUNITY (2009)
Biomarkers: Diagnosis and Risk Assessment in Sepsis
Corey E. Ventetuolo et al.
CLINICS IN CHEST MEDICINE (2008)
Predictors for failed dose reduction of inhaled corticosteroids in childhood asthma
Albert M. Li et al.
RESPIROLOGY (2008)
Immunology of asthma and chronic obstructive pulmonary disease
Peter J. Barnes
NATURE REVIEWS IMMUNOLOGY (2008)
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma
Mike Berry et al.
THORAX (2007)
Factors affecting exhaled nitric oxide measurements: the effect of sex
D. Robin Taylor et al.
RESPIRATORY RESEARCH (2007)
Predicting and evaluating response to omalizumab in patients with severe allergic asthma
J. Bousquet et al.
RESPIRATORY MEDICINE (2007)
Regulatory role of pro-Th1 and pro-Th2 cytokines in modulating the activity of Th1 and Th2 cells when B cell and macrophages are used as antigen presenting cells
Vinod Singh et al.
BMC IMMUNOLOGY (2006)
Total serum immunoglobulin E levels in a case-control study in asthmatic/allergic patients, their family members, and healthy subjects from India
S. Sharma et al.
CLINICAL AND EXPERIMENTAL ALLERGY (2006)
Effects of smoking cessation on lung function and airway inflammation in smokers with asthma
Rekha Chaudhuri et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)
The role of the mast cell in the pathophysiology of asthma
P Bradding et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)
Low-dose inhaled and nasal corticosteroid use and the risk of cataracts
P. Ernst et al.
EUROPEAN RESPIRATORY JOURNAL (2006)
Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivity
J Reisinger et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)
Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids
A Deykin et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)
Epithelial inducible nitric oxide synthase activity is the major determinant of nitric oxide concentration in exhaled breath
C Lane et al.
THORAX (2004)
A population based case-control study of cataract and inhaled corticosteroids
L Smeeth et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2003)
The lineage decisions of helper T cells
KM Murphy et al.
NATURE REVIEWS IMMUNOLOGY (2002)
Matricellular proteins: extracellular modulators of cell function
P Bornstein et al.
CURRENT OPINION IN CELL BIOLOGY (2002)
Changes of exhaled nitric oxide during steroid treatment of childhood asthma
J Beck-Ripp et al.
EUROPEAN RESPIRATORY JOURNAL (2002)
Smoking and airway inflammation in patients with mild asthma
GW Chalmers et al.
CHEST (2001)
Omalizumab, anti-IgE recombinant humanized monoclonal antibody, for the treatment of severe allergic asthma
W Busse et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2001)
Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation?
KF Chung
EUROPEAN RESPIRATORY JOURNAL (2000)
Induced sputum cell counts in healthy adults
J Belda et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)