4.6 Review

Treatment Response Biomarkers in Asthma and COPD

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Respiratory System

High eosinophil counts predict decline in FEV1: results from the CanCOLD study

Wan C. Tan et al.

Summary: This study found that older adults with a higher blood eosinophil count have a faster decline in lung function and are associated with undetected structural airway abnormalities.

EUROPEAN RESPIRATORY JOURNAL (2021)

Article Allergy

Sputum TNF markers are increased in neutrophilic and severe asthma and are reduced by azithromycin treatment

Natalie M. Niessen et al.

Summary: This study investigated the association between TNF markers and clinical phenotypes of asthma, as well as the effect of azithromycin treatment on these markers. The results showed dysregulation of TNF markers in the airways related to important asthma phenotypes, with azithromycin treatment significantly reducing TNF levels in non-eosinophilic participants.

ALLERGY (2021)

Review Respiratory System

Neutrophils in asthma: the good, the bad and the bacteria

Helena Crisford et al.

Summary: Airway inflammation in asthma is complex, with a subset of patients having an increased proportion of neutrophils in their airways, leading to poor response to traditional therapies. Neutrophils, comprising a significant portion of white blood cells, play a critical role in inflammatory and infectious challenges but their functions change with age. This highlights the need for personalized therapeutic strategies for asthma patients based on their age and type of airway inflammation.

THORAX (2021)

Article Respiratory System

A Comprehensive Analysis of the Stability of Blood Eosinophil Levels

Bradley E. Chipps et al.

Summary: Intrinsic, extrinsic, and technical factors can influence the clinical interpretation of eosinophil counts, and a single measurement may not be sufficient when using eosinophil counts for the diagnosis and management of eosinophilic asthma.

ANNALS OF THE AMERICAN THORACIC SOCIETY (2021)

Article Allergy

Dupilumab Efficacy in Patients with Uncontrolled, Moderate-to-Severe Allergic Asthma

Jonathan Corren et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2020)

Review Allergy

Anti-IL5 Therapies for Severe Eosinophilic Asthma: Literature Review and Practical Insights

Francesco Menzella et al.

JOURNAL OF ASTHMA AND ALLERGY (2020)

Review Biochemistry & Molecular Biology

The Airway Epithelium-A Central Player in Asthma Pathogenesis

Jenny Calven et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Allergy

Periostin: An emerging biomarker for allergic diseases

Kenji Izuhara et al.

ALLERGY (2019)

Editorial Material Respiratory System

Neutrophilic asthma: welcome back!

Peter G. Gibson et al.

EUROPEAN RESPIRATORY JOURNAL (2019)

Article Allergy

Lower airway microbiota associates with inflammatory phenotype in severe preschool wheeze

Polly F. M. Robinson et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)

Article Respiratory System

Do blood eosinophils strictly reflect airway inflammation in COPD? Comparison with asthmatic patients

Patrizia Pignatti et al.

RESPIRATORY RESEARCH (2019)

Article Allergy

Prospective predictors of exacerbation status in severe asthma over a 3-year follow-up

H. Kimura et al.

CLINICAL AND EXPERIMENTAL ALLERGY (2018)

Article Allergy

Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease

Jeong H. Yun et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Article Allergy

Inflammatory phenotypes in patients with severe asthma are associated with distinct airway microbiology

Steven L. Taylor et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2018)

Article Medicine, General & Internal

Once-Daily Single-Inhaler Triple versus Dual Therapy in Patients with COPD

David A. Lipson et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Allergy

Relationship of Blood Eosinophil Count to Exacerbations in Chronic Obstructive Pulmonary Disease

Robert S. Zeiger et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2018)

Article Respiratory System

Clinical utility of fractional exhaled nitric oxide and blood eosinophils counts in the diagnosis of asthma-COPD overlap

Yusuke Takayama et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2018)

Article Respiratory System

Blood eosinophils: a biomarker of COPD exacerbation reduction with inhaled corticosteroids

Salman H. Siddiqui et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2018)

Review Infectious Diseases

Antibiotic resistance: a rundown of a global crisis

Bilal Aslam et al.

INFECTION AND DRUG RESISTANCE (2018)

Article Respiratory System

Evaluation of Systemic Corticosteroids in Patients With an Acute Exacerbation of COPD and a Diagnosis of Pneumonia

Tyler Scholl et al.

CHRONIC OBSTRUCTIVE PULMONARY DISEASES-JOURNAL OF THE COPD FOUNDATION (2018)

Review Allergy

Non-eosinophilic asthma: current perspectives

Ignacio Esteban-Gorgojo et al.

JOURNAL OF ASTHMA AND ALLERGY (2018)

Article Respiratory System

FeNO-based asthma management results in faster improvement of airway hyperresponsiveness

Katrine Feldballe Bernholm et al.

ERJ OPEN RESEARCH (2018)

Review Allergy

Novel monoclonal treatments in severe asthma

Howraman Meteran et al.

JOURNAL OF ASTHMA (2017)

Article Medicine, General & Internal

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease

I. D. Pavord et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study

Akbar K. Waljee et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Article Medicine, General & Internal

Short term use of oral corticosteroids and related harms among adults in the United States: population based cohort study

Akbar K. Waljee et al.

BMJ-BRITISH MEDICAL JOURNAL (2017)

Review Medicine, General & Internal

Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections

Philipp Schuetz et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)

Review Medicine, General & Internal

Tailored interventions based on sputum eosinophils versus clinical symptoms for asthma in children and adults

Helen L. Petsky et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2017)

Letter Critical Care Medicine

Eosinophilia, Frequent Exacerbations, and Steroid Response in Chronic Obstructive Pulmonary Disease

Peter M. A. Calverley et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)

Article Critical Care Medicine

Allergen-induced Increases in Sputum Levels of Group 2 Innate Lymphoid Cells in Subjects with Asthma

Ruchong Chen et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)

Article Respiratory System

Personalised medicine in asthma: time for action

Kian Fan Chung

EUROPEAN RESPIRATORY REVIEW (2017)

Article Critical Care Medicine

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report

Claus F. Vogelmeier et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)

Article Critical Care Medicine

Eosinophils in COPD Exacerbations Are Associated With Increased Readmissions

Simon Couillard et al.

Article Respiratory System

Effect of treatment with inhaled corticosteroid on serum periostin levels in asthma

Makoto Hoshino et al.

RESPIROLOGY (2016)

Review Pharmacology & Pharmacy

Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease

Leena George et al.

THERAPEUTIC ADVANCES IN CHRONIC DISEASE (2016)

Article Critical Care Medicine

Blood Eosinophils and Exacerbations in Chronic Obstructive Pulmonary Disease The Copenhagen General Population Study

Signe Vedel-Krogh et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)

Article Critical Care Medicine

Blood Eosinophils and Outcomes in Severe Hospitalized Exacerbations of COPD

Mona Bafadhel et al.

Meeting Abstract Allergy

Response to Omalizumab Therapy Based on Level of IgE: A Two Year Observational Study (REALITY Study)

Jay Peters et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

Article Allergy

Inflammatory mechanisms in patients with chronic obstructive pulmonary disease

Peter J. Barnes

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2016)

Article Medicine, General & Internal

Estimating National Trends in Inpatient Antibiotic Use Among US Hospitals From 2006 to 2012

James Baggs et al.

JAMA INTERNAL MEDICINE (2016)

Article Respiratory System

Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD

Netsanet A. Negewo et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2016)

Review Respiratory System

Therapeutic implications of 'neutrophilic asthma'

Parameswaran Nair et al.

CURRENT OPINION IN PULMONARY MEDICINE (2015)

Article Respiratory System

Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort

Dominick E. Shaw et al.

EUROPEAN RESPIRATORY JOURNAL (2015)

Article Respiratory System

The utility of inflammatory markers to predict readmissions and mortality in COPD cases with or without eosinophilia

Dildar Duman et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2015)

Article Allergy

Markers of Differential Response to Inhaled Corticosteroid Treatment Among Children with Mild Persistent Asthma

Joe K. Gerald et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE (2015)

Article Respiratory System

Effects of weight loss on asthma control in obese patients with severe asthma

Servulo Azevedo Dias-Junior et al.

EUROPEAN RESPIRATORY JOURNAL (2014)

Article Respiratory System

Importance of concomitant local and systemic eosinophilia in uncontrolled asthma

Florence Nicole Schleich et al.

EUROPEAN RESPIRATORY JOURNAL (2014)

Article Medicine, General & Internal

Outdoor air pollution and asthma

Michael Guarnieri et al.

LANCET (2014)

Article Medicine, General & Internal

Withdrawal of Inhaled Glucocorticoids and Exacerbations of COPD

Helgo Magnussen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Medicine, General & Internal

Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary disease

Julia A. E. Walters et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2014)

Review Medicine, General & Internal

Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease

Kayleigh M. Kew et al.

COCHRANE DATABASE OF SYSTEMATIC REVIEWS (2014)

Article Allergy

Biomarker surrogates do not accurately predict sputum eosinophil and neutrophil percentages in asthmatic subjects

Annette T. Hastie et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

Letter Allergy

Lysis of primed eosinophils in severe asthma

Carl Persson

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)

Article Biotechnology & Applied Microbiology

Systemic Inflammation Is Associated with Differential Gene Expression and Airway Neutrophilia in Asthma

Juan-juan Fu et al.

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY (2013)

Article Respiratory System

Relationship between airway neutrophilia and ageing in asthmatics and non-asthmatics

Collin R. Brooks et al.

RESPIROLOGY (2013)

Article Critical Care Medicine

Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease A Randomized Placebo-Controlled Trial

Mona Bafadhel et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)

Article Critical Care Medicine

A Large Subgroup of Mild-to-Moderate Asthma Is Persistently Noneosinophilic

Kelly Wong McGrath et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)

Article Critical Care Medicine

An Official ATS Clinical Practice Guideline: Interpretation of Exhaled Nitric Oxide Levels (FENO) for Clinical Applications

Raed A. Dweik et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Pharmacology & Pharmacy

Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgE

Philip J. Lowe et al.

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2011)

Article Respiratory System

Different inflammatory phenotypes in adults and children with acute asthma

F. Wang et al.

EUROPEAN RESPIRATORY JOURNAL (2011)

Article Medicine, General & Internal

Lebrikizumab Treatment in Adults with Asthma

Jonathan Corren et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Respiratory System

Lower FEV1 in non-COPD, nonasthmatic subjects: association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes

Hironori Masuko et al.

INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE (2011)

Article Critical Care Medicine

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

Wendy C. Moore et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)

Article Allergy

Eosinophil protein in airway macrophages: A novel biomarker of eosinophilic inflammation in patients with asthma

Neeta S. Kulkarni et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2010)

Review Immunology

Innate Cells and T Helper 2 Cell Immunity in Airway Inflammation

Nora A. Barrett et al.

IMMUNITY (2009)

Review Respiratory System

Biomarkers: Diagnosis and Risk Assessment in Sepsis

Corey E. Ventetuolo et al.

CLINICS IN CHEST MEDICINE (2008)

Review Immunology

Immunology of asthma and chronic obstructive pulmonary disease

Peter J. Barnes

NATURE REVIEWS IMMUNOLOGY (2008)

Article Respiratory System

Factors affecting exhaled nitric oxide measurements: the effect of sex

D. Robin Taylor et al.

RESPIRATORY RESEARCH (2007)

Article Cardiac & Cardiovascular Systems

Predicting and evaluating response to omalizumab in patients with severe allergic asthma

J. Bousquet et al.

RESPIRATORY MEDICINE (2007)

Article Critical Care Medicine

Effects of smoking cessation on lung function and airway inflammation in smokers with asthma

Rekha Chaudhuri et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)

Article Allergy

The role of the mast cell in the pathophysiology of asthma

P Bradding et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2006)

Article Respiratory System

Low-dose inhaled and nasal corticosteroid use and the risk of cataracts

P. Ernst et al.

EUROPEAN RESPIRATORY JOURNAL (2006)

Article Allergy

Sputum eosinophil counts predict asthma control after discontinuation of inhaled corticosteroids

A Deykin et al.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2005)

Article Ophthalmology

A population based case-control study of cataract and inhaled corticosteroids

L Smeeth et al.

BRITISH JOURNAL OF OPHTHALMOLOGY (2003)

Review Immunology

The lineage decisions of helper T cells

KM Murphy et al.

NATURE REVIEWS IMMUNOLOGY (2002)

Review Cell Biology

Matricellular proteins: extracellular modulators of cell function

P Bornstein et al.

CURRENT OPINION IN CELL BIOLOGY (2002)

Article Respiratory System

Changes of exhaled nitric oxide during steroid treatment of childhood asthma

J Beck-Ripp et al.

EUROPEAN RESPIRATORY JOURNAL (2002)

Article Critical Care Medicine

Smoking and airway inflammation in patients with mild asthma

GW Chalmers et al.

Article Respiratory System

Airway smooth muscle cells: contributing to and regulating airway mucosal inflammation?

KF Chung

EUROPEAN RESPIRATORY JOURNAL (2000)

Article Critical Care Medicine

Induced sputum cell counts in healthy adults

J Belda et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2000)